ID Q581P5_9TRYP Unreviewed; 1079 AA.
AC Q581P5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 22-FEB-2023, entry version 37.
DE RecName: Full=CRAL-TRIO domain-containing protein {ECO:0000259|PROSITE:PS50191};
GN ORFNames=Tb04.30K5.40 {ECO:0000313|EMBL:AAX80058.1};
OS Trypanosoma brucei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=5691 {ECO:0000313|EMBL:AAX80058.1};
RN [1] {ECO:0000313|EMBL:AAX80058.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GUTat10.1 {ECO:0000313|EMBL:AAX80058.1};
RA Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L.,
RA Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J.,
RA Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G.,
RA Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O.,
RA Wortman J., Fraser C.M., El-Sayed N.M.A.;
RL Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAX80058.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GUTat10.1 {ECO:0000313|EMBL:AAX80058.1};
RA El-Sayed N.M., Khalak H., Adams M.D.;
RL Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAX80058.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GUTat10.1 {ECO:0000313|EMBL:AAX80058.1};
RA Haas B., Blandin G., El-Sayed N.;
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AC091781; AAX80058.1; -; Genomic_DNA.
DR AlphaFoldDB; Q581P5; -.
DR EnsemblProtists; AAZ10983; AAZ10983; Tb927.4.3920.
DR VEuPathDB; TriTrypDB:Tb1125.4.3920; -.
DR VEuPathDB; TriTrypDB:Tb427_040042100; -.
DR VEuPathDB; TriTrypDB:Tb927.4.3920; -.
DR VEuPathDB; TriTrypDB:Tbg972.4.4030; -.
DR HOGENOM; CLU_286459_0_0_1; -.
DR OMA; YHRYPVC; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR PANTHER; PTHR46384:SF2; CRAL-TRIO DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46384; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 422..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 593..615
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 621..639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 651..673
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 679..701
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 713..732
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 738..754
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 766..786
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 86..237
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
SQ SEQUENCE 1079 AA; 121768 MW; EDFE5FBABCF07DF3 CRC64;
MSSFLQELGP VAVSHRQELE EVKRELDIKR DELDCWIYGF LENKKFDVKE TVAKLQRRFA
MEVNEMAKYE FTEYMRTSLR LGIIQVIGED KCGRTIFYVT VNRDKKAASH RDGKKHTFDL
MVSYGTRLRA DNKRCQMVLL VNYEDASMWS NVDMSLQADV ALRISKFFPG CISKVYICNM
GRMLCSVAKP LFSQLPSAFS DSIMFFSKSD RASGRLLEFI DESVLPVQLG GTNDCDNQEH
WDRHGDIIED YYHGMKAAIS ERGLTVKEWE LQCIEQPNVP VRHPSLASET ESMVSLLTFG
SSLTATPVEG NLNGMWRHDN DISPPLEEEE NEWCLLMKPL PNNLSLFFLE ELYRWRVAVS
AEEGEMRCAL MDDYAAAWKR EFDELPMLDL SNKKWYRFIP ESLRELYHGV LIVVNVASSL
SFLVALLFFM ALTSSAAVTV FLAFFIEWNY VYALFATLIL VTFQGTALCS RAVTVLVVIM
KHKVVPPLDM LGKTRGSVAQ LILFCSMIFL QMFSFGYSMT HSSLLRSIQV TFATGWLFAV
AFLALCHIVL FFDWIPMGEQ RRKKNQGSML ALYLLLDVQE SEEKTEAVLT RRLSTTIACA
VPITLDFLLG IAFIISGMIP FAVATCIATV AAILTIDYCS LGRSSMSSRS VLRSTVAFAC
MLWLYLCFSF RFLQYDGPWI VSVCTVAAVN VVFISLAVFC LRKRSAKKTL RGLLFLFVIL
LITSCTASFF LVGSTVGVIS LVLLIHSGMG IFCVRRRSRN IGGTFIFYGA LAMLALSCVL
LGWLGAKWQY WVPHSLPPVN ASGPRDPLEE YHQYPICTLR TAGGFGIVDF ALLTEVSGAS
KENVFHEDFD NWFGSTDVVY NNTVKVYGER NEQWSISRFD SLARNVTVLT LQNGRVYSSI
ITMTVWIGYI ALAPLQILLP NNWLKQVAFL LSFLTRAIDF TWYDVKDEVV RYLTEMKNTT
SNEIVLTAWG IAGGIASLAG VESHTQTITF GSPGLMDALH YTNYTEGEYH KYVLAVVSEL
DVLNAVTRYD PTTYQRIQCS AGSNTCGSMN YISSELVRVC DTTGRRHVGQ QVEESVHEM
//
