ID Q5CCN8_9ALPH Unreviewed; 532 AA.
AC Q5CCN8;
DT 12-APR-2005, integrated into UniProtKB/TrEMBL.
DT 12-APR-2005, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Transcriptional activator {ECO:0000313|EMBL:BAD91096.1};
GN Name=ORF63 {ECO:0000313|EMBL:BAD91096.1};
OS Equid alphaherpesvirus 1 (Equine herpesvirus 1).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Orthoherpesviridae; Alphaherpesvirinae; Varicellovirus;
OC Varicellovirus equidalpha1.
OX NCBI_TaxID=10326 {ECO:0000313|EMBL:BAD91096.1};
RN [1] {ECO:0000313|EMBL:BAD91096.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=89c104 {ECO:0000313|EMBL:BAD91096.1};
RA Ibrahim E.M., Kubota T., Matsumura T., Kennedy M.A., Allen G.P.,
RA Yamaguchi T., Fukushi H.;
RT "Genomic variation in Equine Herpesvirus Type 1 Isolated from Onager,
RT Zebra, and Gazelle.";
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AB194262; BAD91096.1; -; Genomic_DNA.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0039648; P:modulation by symbiont of host protein ubiquitination; IEA:UniProtKB-KW.
DR CDD; cd23130; RING-HC_EHV1-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047126; RNF141-like.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR12109:SF3; RING FINGER PROTEIN 141; 1.
DR PANTHER; PTHR12109; RING FINGER PROTEIN 141-RELATED; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022711};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Modulation of host ubiquitin pathway by viral E3 ligase
KW {ECO:0000256|ARBA:ARBA00022711};
KW Modulation of host ubiquitin pathway by virus
KW {ECO:0000256|ARBA:ARBA00022662}; Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 8..47
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 206..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 460..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..241
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..279
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 532 AA; 58628 MW; 651D647123DE1AF9 CRC64;
MATVAERCPI CLEDPSNYSM ALPCLHAFCY VCITRWIRQN PTCPLCKVPV ESVVHTIESD
SEFKETKVSV DFDYDSEEDE DSFEGQFLAV DSGDAPANIS AWNGPMAFVP LNANGTAGAP
RLQPLVDWLV ERLDQLFETP ELALVMRNIV MDTLCEHGCN EEELTRQFWP MFHEDTVPFV
ADLIVQAELC VASRPILPIA RGRGVEYIDS SSSSSSSEEE TDSDIEVDPN NLTDPEDTSD
ETSTDNSSAQ APRQEDSRPA RARPGPPTRG RRRGRRPAAP GPASRRSARL RRRQPRTNSR
TNGGDNGEII DLTLDSDGDT EPADVSGSLN TTDQPVLIPD EEEAAPASPH TSSNSAIICL
VSELTPESEE PPRDQPVAPS GSSAGERPMR PRCSLREFAR RFMALAPRDS STSEAVGPSR
LGAGPRATEP FSVAVVLVDR SSEGAGLFGG RFAQHVRRRT EDESARRRGN VLLRPRRQSV
PPVPYPDIAS TSPLIRQGGQ RVRDLQRAFQ TQPAEPEEMR CPHNCQRYRR NQ
//
