ID Q5CWC3_CRYPI Unreviewed; 456 AA.
AC Q5CWC3;
DT 12-APR-2005, integrated into UniProtKB/TrEMBL.
DT 12-APR-2005, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Transcription initiation factor TFIIB Sua7p ZnR+2cyclins {ECO:0000313|EMBL:EAK89316.1};
GN ORFNames=cgd8_880 {ECO:0000313|EMBL:EAK89316.1};
OS Cryptosporidium parvum (strain Iowa II).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=353152 {ECO:0000313|EMBL:EAK89316.1, ECO:0000313|Proteomes:UP000006726};
RN [1] {ECO:0000313|EMBL:EAK89316.1, ECO:0000313|Proteomes:UP000006726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Iowa II {ECO:0000313|Proteomes:UP000006726};
RX PubMed=15044751; DOI=10.1126/science.1094786;
RA Abrahamsen M.S., Templeton T.J., Enomoto S., Abrahante J.E., Zhu G.,
RA Lancto C.A., Deng M., Liu C., Widmer G., Tzipori S., Buck G.A., Xu P.,
RA Bankier A.T., Dear P.H., Konfortov B.A., Spriggs H.F., Iyer L.,
RA Anantharaman V., Aravind L., Kapur V.;
RT "Complete genome sequence of the apicomplexan, Cryptosporidium parvum.";
RL Science 304:441-445(2004).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAK89316.1}.
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DR EMBL; AAEE01000003; EAK89316.1; -; Genomic_DNA.
DR RefSeq; XP_626996.1; XM_626996.1.
DR AlphaFoldDB; Q5CWC3; -.
DR STRING; 353152.Q5CWC3; -.
DR EnsemblProtists; EAK89316; EAK89316; cgd8_880.
DR GeneID; 3374417; -.
DR KEGG; cpv:cgd8_880; -.
DR VEuPathDB; CryptoDB:cgd8_880; -.
DR InParanoid; Q5CWC3; -.
DR OMA; DHDQRMK; -.
DR OrthoDB; 38673at2759; -.
DR Proteomes; UP000006726; Chromosome 8.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR Gene3D; 1.10.472.170; -; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 1.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR000812; TFIIB.
DR InterPro; IPR013150; TFIIB_cyclin.
DR InterPro; IPR013137; Znf_TFIIB.
DR PANTHER; PTHR11618:SF13; TRANSCRIPTION INITIATION FACTOR IIB; 1.
DR PANTHER; PTHR11618; TRANSCRIPTION INITIATION FACTOR IIB-RELATED; 1.
DR Pfam; PF08271; TF_Zn_Ribbon; 1.
DR Pfam; PF00382; TFIIB; 2.
DR PRINTS; PR00685; TIFACTORIIB.
DR SUPFAM; SSF47954; Cyclin-like; 2.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS51134; ZF_TFIIB; 1.
PE 4: Predicted;
KW Initiation factor {ECO:0000313|EMBL:EAK89316.1};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Protein biosynthesis {ECO:0000313|EMBL:EAK89316.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006726};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00469}.
FT DOMAIN 148..181
FT /note="TFIIB-type"
FT /evidence="ECO:0000259|PROSITE:PS51134"
FT REGION 63..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 456 AA; 50218 MW; B332DE05A7E445AC CRC64;
MNSDLSSSGV NTNLNIAGNV NSLVDTQNMS SSQANGISSV GNRMDNLTIN NTSAASNTIN
LQRSQLGNST DGLTGGPIRS SDKLLSDKQN DLGRSNPYPE RKIQQTIGES EPTQQVPAIP
ATIQAGIVSN KDFDKPGALP HLFRSFRATK FCKRCGAGNS IVVYDSKSGS EICTRCGVVV
EDRVINEEQE WRSFSNDGND GNSKSRIGSV NDVWLDDGTD SQLLVGDKKL MKTMLKHNTQ
ASSDRMIKEV FNQLRQIANS FSLHDNIIER CKEIVKEQSN LNILKSGKKH VLAIVYLACR
EEGVSRTVKE LLSFDRTISE RELVRSINKL KKDLPRRGPT LSSSAAELMP RFCHYLQLSH
EIVGIAEYVC RTAEQYINKS HRPNSLAAGA IYFVCNLCNI QIEMKSVAVA AKSGETTVRG
VYKELLLVGE KLLPSDFTPK LVGGIDTLKR RSKIFE
//
