ID   Q5D8K5_SCHJA            Unreviewed;       753 AA.
AC   Q5D8K5;
DT   29-MAR-2005, integrated into UniProtKB/TrEMBL.
DT   29-MAR-2005, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=SJCHGC02198 protein {ECO:0000313|EMBL:AAW27851.1};
OS   Schistosoma japonicum (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6182 {ECO:0000313|EMBL:AAW27851.1};
RN   [1] {ECO:0000313|EMBL:AAW27851.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Han Z.;
RT   "The full-length cDNA sequences of Schistosoma japonicum genes.";
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AAW27851.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=16617374; DOI=10.1371/journal.ppat.0020029;
RA   Liu F., Lu J., Hu W., Wang S.Y., Cui S.J., Chi M., Yan Q., Wang X.R.,
RA   Song H.D., Xu X.N., Wang J.J., Zhang X.L., Zhang X., Wang Z.Q., Xue C.L.,
RA   Brindley P.J., McManus D.P., Yang P.Y., Feng Z., Chen Z., Han Z.G.;
RT   "New perspectives on host-parasite interplay by comparative transcriptomic
RT   and proteomic analyses of Schistosoma japonicum.";
RL   PLoS Pathog. 2:268-281(2006).
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DR   EMBL; AY816119; AAW27851.1; -; mRNA.
DR   AlphaFoldDB; Q5D8K5; -.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          1..65
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   DOMAIN          444..597
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   753 AA;  86671 MW;  FE35BB92DF702025 CRC64;
     MDTMLANSPG VAVYLDDVIV TGSSKSELFN RLDSVLTKIS EYGFYLKEEK CTFFMDSVKY
     LGFIFDKNGR HPDPENVRAI QNMPPPSNVA TLRSFLGLIS YYSNFLPQLH RLRAPMNHLL
     SNNIKWNWST ECQKSFDKVK SLLASDLLLT YFDPSLEIVV AADASDYGIG AVISHRFPDD
     KEKAIAHASR TLTPVERKYS QIEKEGSALI FAVKKFHKML HGRKFTLLTD HKPLLSIFGS
     KKGIPVYTAN RLQRWATMLL GYDFTIKYKS TSDFGHADAL SRLMSNHKPE DEDTVIASIS
     VEEDVSSTLN NSTQILPMTA ARVADHTRRD PTLQQLATFL RRGWPPRLTS QELKQYYQRR
     QSLSIVNDCI MFADRVVVPN NLRSHVLKQL HTAHPGIGRM KAIARSYVYW PNIDKDIEDL
     VRGCIKCAAA SKHPRKAELH SWSSEKQPWS RIHLDFAGPF QGTYFLVCVD AYSKWPEIFP
     MHHITSQATT VKLRHLFSRF GVPDVLVTDN GTQFTSSIFS QFCGKFGVKH VRAPPYHPQS
     NGQAERFVDT FKRALLKAKG EGKIKEILDD FLLIYRTTPN PSAPNHLSPA EIMFGRKVKT
     TLDAIKPKQI DKGRRNRKME TQFNRHHGTR RRVFQINQKV YVRDFRYSPP QWTSGRILKR
     RGSVMYVVDV EGLKWVRHAN HILEHAAACH ETERLNTLWE IFLDSFDMEN VATKRNAQLE
     QNPVRRSMRK RRRPEILQVD PKRRAYVSED RYQ
//