ID   Q5F3S6_CHICK            Unreviewed;       650 AA.
AC   Q5F3S6; F1NN51;
DT   15-MAR-2005, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2005, sequence version 1.
DT   27-MAR-2024, entry version 125.
DE   RecName: Full=Agenet-like domain-containing protein {ECO:0000259|PROSITE:PS51641};
GN   ORFNames=RCJMB04_7n20 {ECO:0000313|EMBL:CAH65208.1};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031 {ECO:0000313|EMBL:CAH65208.1};
RN   [1] {ECO:0000313|EMBL:CAH65208.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CB {ECO:0000313|EMBL:CAH65208.1};
RC   TISSUE=Bursa {ECO:0000313|EMBL:CAH65208.1};
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, Cytoplasmic ribonucleoprotein granule
CC       {ECO:0000256|ARBA:ARBA00004331}.
CC   -!- SIMILARITY: Belongs to the FMR1 family.
CC       {ECO:0000256|ARBA:ARBA00006633}.
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DR   EMBL; AJ851574; CAH65208.1; -; mRNA.
DR   RefSeq; NP_001012619.1; NM_001012601.2.
DR   AlphaFoldDB; Q5F3S6; -.
DR   PaxDb; 9031-ENSGALP00000014383; -.
DR   GeneID; 424968; -.
DR   KEGG; gga:424968; -.
DR   CTD; 8087; -.
DR   VEuPathDB; HostDB:geneid_424968; -.
DR   eggNOG; ENOG502QPKJ; Eukaryota.
DR   HOGENOM; CLU_020699_3_0_1; -.
DR   PRO; PR:Q5F3S6; -.
DR   Bgee; ENSGALG00000008864; Expressed in spermatid and 13 other cell types or tissues.
DR   ExpressionAtlas; Q5F3S6; baseline and differential.
DR   GO; GO:0036464; C:cytoplasmic ribonucleoprotein granule; IEA:UniProtKB-SubCell.
DR   GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:InterPro.
DR   CDD; cd22504; KH_I_FXR1_rpt1; 1.
DR   CDD; cd22507; KH_I_FXR1_rpt2; 1.
DR   CDD; cd22510; KH_I_FXR1_rpt3; 1.
DR   CDD; cd20472; Tudor_Agenet_FXR1_rpt1; 1.
DR   CDD; cd20475; Tudor_Agenet_FXR1_rpt2; 1.
DR   Gene3D; 2.30.30.140; -; 2.
DR   Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR   InterPro; IPR008395; Agenet-like_dom.
DR   InterPro; IPR040148; FMR1.
DR   InterPro; IPR022034; FMR1-like_C_core.
DR   InterPro; IPR040472; FMRP_KH0.
DR   InterPro; IPR032172; FXR1_C1.
DR   InterPro; IPR032177; FXR_C3.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR047494; KH_I_FXR1_rpt1.
DR   InterPro; IPR047495; KH_I_FXR1_rpt2.
DR   InterPro; IPR047496; KH_I_FXR1_rpt3.
DR   InterPro; IPR047425; Tudor_Agenet_FXR1_rpt1.
DR   InterPro; IPR047427; Tudor_Agenet_FXR1_rpt2.
DR   InterPro; IPR041560; Tudor_FRM1.
DR   PANTHER; PTHR10603; FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN; 1.
DR   PANTHER; PTHR10603:SF6; FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN 1; 1.
DR   Pfam; PF05641; Agenet; 1.
DR   Pfam; PF12235; FXMRP1_C_core; 1.
DR   Pfam; PF16096; FXR_C1; 1.
DR   Pfam; PF16097; FXR_C3; 1.
DR   Pfam; PF00013; KH_1; 2.
DR   Pfam; PF17904; KH_9; 1.
DR   Pfam; PF18336; Tudor_FRX1; 1.
DR   SMART; SM00322; KH; 2.
DR   SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR   PROSITE; PS51641; AGENET_LIKE; 2.
DR   PROSITE; PS50084; KH_TYPE_1; 2.
PE   2: Evidence at transcript level;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Myogenesis {ECO:0000256|ARBA:ARBA00022541};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00117}.
FT   DOMAIN          4..50
FT                   /note="Agenet-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51641"
FT   DOMAIN          63..115
FT                   /note="Agenet-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51641"
SQ   SEQUENCE   650 AA;  72812 MW;  356B4EA404C9DEE0 CRC64;
     MEELTVEVRG SNGAFYKGFI KDVHEDSLTV VFENNWQPER QVPFNEVRLP PPPDIKKEIG
     EGDEVEVYSR ANDQEPCGWW LAKVRMMKGE FYVIEYAACD ATYNEIVTYE RLRPVNQNKT
     VKKNTFFKCT VDVPEDLRDA CANENAHKDF KKAVGACRIF YHAETAQLII LSASEATVKR
     VNILSDMHLR SIRTKLMLMS RNEEATKHLE CTKQLAAAFH EEFVVREDLM GLAIGTHGSN
     IQQARKVPGV TAIELEEDTG TFRIYGETAD AVKKARSYLE FVEDFIQVPR NLVGKVIGKN
     GKVIQEIVDK SGVVRVRIEG DNENKLPRED GMVPFVFVGT KESIGNVQVL LEYHIAYLKE
     VEQLRLERLQ IDEQLRQIGM GFRPSSARVP EKEKGYTTDE STLSSVQGSR SYSGRGRGRR
     GPSYTSGYGT NSELSNPSET ESERKDELSD WSLAGEDDRE SRHQRDNRRR PGGRGRSVSG
     GRGRGGPRGG KSSISSVLKD PDSNPYSLLD NTESDQTVDT DASESHHSSN RRRRSRRRRT
     DEDAVLMDGM TESDTASVNE NGLVTVADYI SRAESQSRQR NPPKETLGKT KKEATKDTID
     ENSPSEKAVN GPATPAVDEP SKLQHSPDEK KVTVQEEGNN QEEAVLNGVS
//