ID Q5F957_NEIG1 Unreviewed; 979 AA.
AC Q5F957;
DT 15-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Restriction endonuclease EcoPI subunit R {ECO:0000313|EMBL:AAW89280.1};
GN ORFNames=NGO_0546 {ECO:0000313|EMBL:AAW89280.1};
OS Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=242231 {ECO:0000313|EMBL:AAW89280.1, ECO:0000313|Proteomes:UP000000535};
RN [1] {ECO:0000313|Proteomes:UP000000535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700825 / FA 1090 {ECO:0000313|Proteomes:UP000000535};
RA Lewis L.A., Gillaspy A.F., McLaughlin R.E., Gipson M., Ducey T.F.,
RA Ownbey T., Hartman K., Nydick C., Carson M.B., Vaughn J., Thomson C.,
RA Song L., Lin S., Yuan X., Najar F., Zhan M., Ren Q., Zhu H., Qi S.,
RA Kenton S.M., Lai H., White J.D., Clifton S., Roe B.A., Dyer D.W.;
RT "The complete genome sequence of Neisseria gonorrhoeae.";
RL Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AE004969; AAW89280.1; -; Genomic_DNA.
DR RefSeq; WP_003689015.1; NC_002946.2.
DR RefSeq; YP_207692.1; NC_002946.2.
DR AlphaFoldDB; Q5F957; -.
DR STRING; 242231.NGO_0546; -.
DR REBASE; 5865; NgoAX.
DR GeneID; 66752885; -.
DR KEGG; ngo:NGO_0546; -.
DR PATRIC; fig|242231.10.peg.644; -.
DR HOGENOM; CLU_011799_1_0_4; -.
DR BRENDA; 3.1.21.5; 3590.
DR Proteomes; UP000000535; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0015668; F:type III site-specific deoxyribonuclease activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR045572; RE_endonuc_C.
DR Pfam; PF19778; RE_endonuc; 1.
DR Pfam; PF04851; ResIII; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:AAW89280.1};
KW Hydrolase {ECO:0000313|EMBL:AAW89280.1};
KW Nuclease {ECO:0000313|EMBL:AAW89280.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000535}.
FT DOMAIN 46..254
FT /note="Helicase/UvrB N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04851"
FT DOMAIN 850..954
FT /note="Type III restriction enzyme C-terminal endonuclease"
FT /evidence="ECO:0000259|Pfam:PF19778"
SQ SEQUENCE 979 AA; 111427 MW; C0E1E3DFD10ECC1A CRC64;
MSGFNYEKNQ PHQMRAVSAV LGVFDGATPK YRTADENPEL LFAAKQYANN ILKVQSQNGI
DGRFPDRSDD QNILDISMET GTGKTYTYTQ TMFELHRWLG VFKFIVVVPT LSIKAGTQQF
LQSKALAEHF EQDFGGDYEG VRLKTYVVES AKKNKGKKSN APITIEQFVK AENKKEIHVL
LINAGMVNSS SMNDTGDKAL KDLFDNPVDA LAAVRPFMIV DEPHKFPTRD SAKTWGNIKR
LKPQYILRYG ATFNDEYYNL LYRLTAVDAF NDGLVKGVRV FQEEMQGGMD AAVKLVSSDG
KEAKFELNEK DKKQTFKLAK GEDLAQIHPA ISDLKIDKMN KTVVVLSNGL ELKTGAVINP
YSYSQTVQDA MMQRAVAEHF KLERALLAER APQPKIKPLT LFFIDDIAGY RSGNELSGSL
KDKFESWIRA EAARRLKTES DPFYRDYLQK TLDDVSACHG GYFSKDNTDS DDRIEQEINE
ILHDKEKLLS LDNPRRFIFS KWTLREGWDN PNVFQICKLR SSGSTTSKLQ EVGRGLRLPV
NELMARVRDV PYKLNYFVDS SEKDFVKQLV GEINDNSFQE EISKKFTEEL KQKILQKYPD
IKPLVLVNQL FSDGIIDDNE NFAEDGYDKL KAAYPEAFPK GLDKGKVSNA KDEGKDTIIM
REGKYEELKA LWELIHHKAV LQYKIKDEAE FVDLFTAYLR ENAAKFPQAG ICTAVNEAYI
NNGLMLSRRI DSIEDEDFIR FNTMTYREFL EKLAQTAKIQ MQTLHQAFYR VRDELNIGDF
LNMQTIAQIK NGFNRFLLHH SFHKFELDYR LVGSKIHPTK FTNKDGKPRA VKKADLGRFE
DTEHRPAAGY LFGEIFYDSD IEHENVANNQ IEGVIVFTKI PRNSIKIPVA GGGTYSPDFA
YIVKTKSGEI LNFVIEAKGT DGAEDLRKSE ERKIKHAEKL FAEISKEIKV VFKTQFDGER
IAELIGQNMP AGGHSENGH
//
