ID Q5FFN6_EHRRG Unreviewed; 181 AA.
AC Q5FFN6;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE RecName: Full=Peptidase A2 domain-containing protein {ECO:0000259|PROSITE:PS50175};
GN OrderedLocusNames=ERGA_CDS_05550 {ECO:0000313|EMBL:CAI28007.1};
OS Ehrlichia ruminantium (strain Gardel).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Ehrlichia.
OX NCBI_TaxID=302409 {ECO:0000313|EMBL:CAI28007.1, ECO:0000313|Proteomes:UP000000533};
RN [1] {ECO:0000313|EMBL:CAI28007.1, ECO:0000313|Proteomes:UP000000533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Gardel {ECO:0000313|EMBL:CAI28007.1,
RC ECO:0000313|Proteomes:UP000000533};
RX PubMed=16547041; DOI=10.1128/JB.188.7.2533-2542.2006;
RA Frutos R., Viari A., Ferraz C., Morgat A., Eychenie S., Kandassamy Y.,
RA Chantal I., Bensaid A., Coissac E., Vachiery N., Demaille J., Martinez D.;
RT "Comparative genomic analysis of three strains of Ehrlichia ruminantium
RT reveals an active process of genome size plasticity.";
RL J. Bacteriol. 188:2533-2542(2006).
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DR EMBL; CR925677; CAI28007.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5FFN6; -.
DR MEROPS; A32.002; -.
DR KEGG; erg:ERGA_CDS_05550; -.
DR HOGENOM; CLU_099411_0_1_5; -.
DR OrthoDB; 7595324at2; -.
DR Proteomes; UP000000533; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd05483; retropepsin_like_bacteria; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR011969; Clan_AA_Asp_peptidase_C.
DR InterPro; IPR001995; Peptidase_A2_cat.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR034122; Retropepsin-like_bacterial.
DR NCBIfam; TIGR02281; clan_AA_DTGA; 1.
DR Pfam; PF13975; gag-asp_proteas; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR PROSITE; PS50175; ASP_PROT_RETROV; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 84..163
FT /note="Peptidase A2"
FT /evidence="ECO:0000259|PROSITE:PS50175"
SQ SEQUENCE 181 AA; 20704 MW; EF09A21D6C1E661A CRC64;
MVGFLESIMQ NVKYILFWFG LIIVVMLFKD ANDDLTSNRY FNKFFSNLGT TQDEIHYTKE
GGAEFYRAKD GHFYITAQIH GVPIKFLVDT GATDVVLSAE DAKQIKDHLK YLNRKKTYHT
ANGTIKALYV EISEMQIGKF VVKDVKASVN VAPMRTSLLG MSFLQYFNFY MSGNTLVLNT
Y
//
