ID Q5FFS4_EHRRG Unreviewed; 673 AA.
AC Q5FFS4;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Similar to competence locus E protein 3 {ECO:0000313|EMBL:CAI28055.1};
GN Name=comEC {ECO:0000313|EMBL:CAI28055.1};
GN OrderedLocusNames=ERGA_CDS_06030 {ECO:0000313|EMBL:CAI28055.1};
OS Ehrlichia ruminantium (strain Gardel).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Ehrlichia.
OX NCBI_TaxID=302409 {ECO:0000313|EMBL:CAI28055.1, ECO:0000313|Proteomes:UP000000533};
RN [1] {ECO:0000313|EMBL:CAI28055.1, ECO:0000313|Proteomes:UP000000533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Gardel {ECO:0000313|EMBL:CAI28055.1,
RC ECO:0000313|Proteomes:UP000000533};
RX PubMed=16547041; DOI=10.1128/JB.188.7.2533-2542.2006;
RA Frutos R., Viari A., Ferraz C., Morgat A., Eychenie S., Kandassamy Y.,
RA Chantal I., Bensaid A., Coissac E., Vachiery N., Demaille J., Martinez D.;
RT "Comparative genomic analysis of three strains of Ehrlichia ruminantium
RT reveals an active process of genome size plasticity.";
RL J. Bacteriol. 188:2533-2542(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CR925677; CAI28055.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5FFS4; -.
DR KEGG; erg:ERGA_CDS_06030; -.
DR HOGENOM; CLU_011826_1_1_5; -.
DR OrthoDB; 9790149at2; -.
DR Proteomes; UP000000533; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR025405; DUF4131.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 48..190
FT /note="DUF4131"
FT /evidence="ECO:0000259|Pfam:PF13567"
FT DOMAIN 236..509
FT /note="ComEC/Rec2-related protein"
FT /evidence="ECO:0000259|Pfam:PF03772"
SQ SEQUENCE 673 AA; 76152 MW; 1599AF756281B975 CRC64;
MDVIITNFIS FLHKQLENNK NSLMLWIPVL QGIGVIIYFS LPTEPQSYIV LCIVFTLFVS
LIAVILKKSN CIFLSLFFIL FGFVTIYVKA HYFSGDVLQA KIYAKDIIGT VKEVSSKQSH
KRVIICDVQN VKYNVTCIRL VSRTQWDENI EIGDKILLSA IVYPPQTAVS PFSYDFSRVS
YFKKINGIGF TISNVRLFEK RKSKKIFEYI ELIRLHIYKL FLRNLTWDTA NVVSALVIGK
KDGISNDIMG NIRNAGIAHL FAISGLHLSF ITGLFFSLSR NLLVFFGNLA ESYNIKKISA
VIAIIVSLIY LLLTGMPVSA ERAFLMTSYV FIGILIDRRH NNFCAIAIAA FIILLCYPEA
VLNPSFQMSF AAVLALIASC DIFTKLIIIG DILQYFSSIV LSSLIAGLAT LPYVIYHFHN
FSIIGVFVNV LAIPITTFFI IPLSLLYVVL SFVNLEFYIS YALESSVKLL LYISNYVSKI
DSLILSFHAV SSVSILVITL GFLFLCLWNG SLRFLGLVVI VCGLFIGFQY VTPDILVNIN
NIAVKESDGQ LYSVNKNAHI TGFIGLVWAK QNGQQKLLKY NLENDKCLFC EAGKGCIYTK
QKRKILIAYT SEYVIQNCLD IDLVIQFGKF VYPQECHKQY LSYVDIISHG PYFIWVLDNK
VKISKHNNRI WNV
//
