ID Q5FLZ7_LACAC Unreviewed; 245 AA.
AC Q5FLZ7;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Acyl-ACP thioesterase {ECO:0000313|EMBL:AAV42277.1};
DE EC=3.1.2.14 {ECO:0000313|EMBL:AAV42277.1};
GN OrderedLocusNames=LBA0386 {ECO:0000313|EMBL:AAV42277.1};
OS Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=272621 {ECO:0000313|Proteomes:UP000006381};
RN [1] {ECO:0000313|EMBL:AAV42277.1, ECO:0000313|Proteomes:UP000006381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700396 / NCK56 / N2 / NCFM
RC {ECO:0000313|Proteomes:UP000006381};
RX PubMed=15671160; DOI=10.1073/pnas.0409188102;
RA Altermann E., Russell W.M., Azcarate-Peril M.A., Barrangou R., Buck B.L.,
RA McAuliffe O., Souther N., Dobson A., Duong T., Callanan M., Lick S.,
RA Hamrick A., Cano R., Klaenhammer T.R.;
RT "Complete genome sequence of the probiotic lactic acid bacterium
RT Lactobacillus acidophilus NCFM.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:3906-3912(2005).
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000256|ARBA:ARBA00004229}.
CC -!- SIMILARITY: Belongs to the acyl-ACP thioesterase family.
CC {ECO:0000256|ARBA:ARBA00006500}.
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DR EMBL; CP000033; AAV42277.1; -; Genomic_DNA.
DR RefSeq; WP_011254136.1; NC_006814.3.
DR RefSeq; YP_193308.1; NC_006814.3.
DR AlphaFoldDB; Q5FLZ7; -.
DR STRING; 272621.LBA0386; -.
DR GeneID; 56941993; -.
DR KEGG; lac:LBA0386; -.
DR PATRIC; fig|272621.13.peg.372; -.
DR eggNOG; COG3884; Bacteria.
DR HOGENOM; CLU_045466_2_0_9; -.
DR OrthoDB; 9801517at2; -.
DR BioCyc; LACI272621:G1G49-380-MONOMER; -.
DR Proteomes; UP000006381; Chromosome.
DR GO; GO:0016297; F:acyl-[acyl-carrier-protein] hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00586; 4HBT; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR InterPro; IPR049427; Acyl-ACP_TE_C.
DR InterPro; IPR002864; Acyl-ACP_thioesterase_NHD.
DR InterPro; IPR045023; FATA/B.
DR InterPro; IPR029069; HotDog_dom_sf.
DR PANTHER; PTHR31727; OLEOYL-ACYL CARRIER PROTEIN THIOESTERASE 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR31727:SF6; OLEOYL-ACYL CARRIER PROTEIN THIOESTERASE 1, CHLOROPLASTIC; 1.
DR Pfam; PF01643; Acyl-ACP_TE; 1.
DR Pfam; PF20791; Acyl-ACP_TE_C; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
PE 3: Inferred from homology;
KW Chloroplast {ECO:0000256|ARBA:ARBA00022528};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AAV42277.1};
KW Plastid {ECO:0000256|ARBA:ARBA00022640};
KW Reference proteome {ECO:0000313|Proteomes:UP000006381};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT DOMAIN 2..119
FT /note="Acyl-ACP thioesterase N-terminal hotdog"
FT /evidence="ECO:0000259|Pfam:PF01643"
FT DOMAIN 150..242
FT /note="Acyl-ACP thioesterase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20791"
SQ SEQUENCE 245 AA; 28987 MW; A5851D1390828B34 CRC64;
MEYKENYQIE FKDCDENRRL KLPALVDLMM QVSEHQLDKR NAGTDDLAQK GLGWVVTQYH
FDIKKMPQAG DQVILSTFAS GYNRFFEYRD FGVSDSAGNP LVVVKSQWVM LNLKERHMVP
ADVKMMEEWG APLLKKMPRF PRLRAQDNYE KKRIYRARYD DLDTNHHVTN SHYFSWFIDM
LDRDFLKNHV VETIDIKFDK EVYYGERVYS CMNLLQNDNI NSSHAIEAED GTVKAICELK
WHEVK
//
