ID COAE_GLUOX Reviewed; 201 AA.
AC Q5FPK0;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 01-MAY-2013, entry version 52.
DE RecName: Full=Dephospho-CoA kinase;
DE EC=2.7.1.24;
DE AltName: Full=Dephosphocoenzyme A kinase;
GN Name=coaE; OrderedLocusNames=GOX1960;
OS Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Gluconobacter.
OX NCBI_TaxID=290633;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=621H;
RX PubMed=15665824; DOI=10.1038/nbt1062;
RA Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F.,
RA Ehrenreich A., Gottschalk G., Deppenmeier U.;
RT "Complete genome sequence of the acetic acid bacterium Gluconobacter
RT oxydans.";
RL Nat. Biotechnol. 23:195-200(2005).
CC -!- FUNCTION: Catalyzes the phosphorylation of the 3'-hydroxyl group
CC of dephosphocoenzyme A to form coenzyme A (By similarity).
CC -!- CATALYTIC ACTIVITY: ATP + 3'-dephospho-CoA = ADP + CoA.
CC -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; CoA from
CC (R)-pantothenate: step 5/5.
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the CoaE family.
CC -!- SIMILARITY: Contains 1 DPCK (dephospho-CoA kinase) domain.
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DR EMBL; CP000009; AAW61696.1; -; Genomic_DNA.
DR RefSeq; YP_192352.1; NC_006677.1.
DR ProteinModelPortal; Q5FPK0; -.
DR STRING; 290633.GOX1960; -.
DR EnsemblBacteria; AAW61696; AAW61696; GOX1960.
DR GeneID; 3249766; -.
DR KEGG; gox:GOX1960; -.
DR PATRIC; 32611840; VBIGluOxy81109_2256.
DR eggNOG; COG0237; -.
DR HOGENOM; HOG000020768; -.
DR KO; K00859; -.
DR OMA; FANFTIR; -.
DR BioCyc; GOXY290633:GHB3-1964-MONOMER; -.
DR UniPathway; UPA00241; UER00356.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR GO; GO:0004140; F:dephospho-CoA kinase activity; IEA:HAMAP.
DR GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:HAMAP.
DR HAMAP; MF_00376; Dephospho_CoA_kinase; 1; -.
DR InterPro; IPR001977; Depp_CoAkinase.
DR Pfam; PF01121; CoaE; 1.
DR TIGRFAMs; TIGR00152; TIGR00152; 1.
DR PROSITE; PS51219; DPCK; 1.
PE 3: Inferred from homology;
KW ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm;
KW Kinase; Nucleotide-binding; Transferase.
FT CHAIN 1 201 Dephospho-CoA kinase.
FT /FTId=PRO_0000243293.
FT DOMAIN 3 201 DPCK.
FT NP_BIND 8 15 ATP (Potential).
SQ SEQUENCE 201 AA; 22297 MW; 870C44F09862F2AD CRC64;
MKIIGLTGGM AAGKSTVAAL FRREGVPVFD ADACVRALQG ERGKALPLIG QAFPGTVVAS
RLDRAALREA VRGRPEALQR LEAIMHPLVR VERERFLKQC RARHEPFCVL DIPLLMEIGE
DRRCDVVMVA EAPMGTRLAR IRQRGRSGGR MSLADAKGLL ARQMSDHERR RRADIVIRTG
LSRGQAVRQV HALLHRLREA S
//
