ID Q5FZU3_ENTGA Unreviewed; 135 AA.
AC Q5FZU3;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE SubName: Full=Vancomycin resistance protein {ECO:0000313|EMBL:AAW65100.1};
DE Flags: Fragment;
GN Name=vanC1 {ECO:0000313|EMBL:AAW65100.1};
OS Enterococcus gallinarum.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1353 {ECO:0000313|EMBL:AAW65100.1};
RN [1] {ECO:0000313|EMBL:AAW65100.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17619103; DOI=10.1007/s00284-005-0484-1;
RA Li S., Zhang Z., Mi Z.H.;
RT "Vancomycin-resistant enterococci in a Chinese hospital.";
RL Curr. Microbiol. 55:125-127(2007).
CC -!- SIMILARITY: Belongs to the D-alanine--D-alanine ligase family.
CC {ECO:0000256|ARBA:ARBA00010871}.
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DR EMBL; AY870597; AAW65100.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5FZU3; -.
DR SMR; Q5FZU3; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR011095; Dala_Dala_lig_C.
DR PANTHER; PTHR23132; D-ALANINE--D-ALANINE LIGASE; 1.
DR PANTHER; PTHR23132:SF25; D-ALANINE--D-ALANINE LIGASE A; 1.
DR Pfam; PF07478; Dala_Dala_lig_C; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409}.
FT DOMAIN 11..94
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAW65100.1"
FT NON_TER 135
FT /evidence="ECO:0000313|EMBL:AAW65100.1"
SQ SEQUENCE 135 AA; 14460 MW; CD1D59375A6CCCDD CRC64;
SALCMNKWLL HQLADTMGIA SAPTLLLSRY ENDPATIDRF IQDHGFPIFI KPNEAGSSKG
ITKVTDKTAL QSALTTAFAY GSTVLIQKAI AGIEIGCGIL GNEQLTIGAC DAISLVDGFF
DFEEKYQLIS ATITT
//
