ID Q5G2U4_9SECO Unreviewed; 2227 AA.
AC Q5G2U4;
DT 01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2005, sequence version 1.
DT 08-NOV-2023, entry version 99.
DE SubName: Full=250 kDa polyprotein {ECO:0000313|EMBL:AAW63128.1};
OS Strawberry latent ringspot virus.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Secoviridae; Stralarivirus; Stralarivirus fragariae.
OX NCBI_TaxID=28351 {ECO:0000313|EMBL:AAW63128.1, ECO:0000313|Proteomes:UP000204336};
RN [1] {ECO:0000313|Proteomes:UP000204336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15664053; DOI=10.1016/j.jviromet.2004.11.006;
RA Tzanetakis I.E., Keller K.E., Martin R.R.;
RT "The use of reverse transcriptase for efficient first- and second-strand
RT cDNA synthesis from single- and double-stranded RNA templates.";
RL J. Virol. Methods 124:73-77(2005).
RN [2] {ECO:0000313|EMBL:AAW63128.1, ECO:0000313|Proteomes:UP000204336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCGR MEN 454.001 {ECO:0000313|EMBL:AAW63128.1};
RX PubMed=16837095; DOI=10.1016/j.virusres.2006.06.001;
RA Tzanetakis I.E., Postman J.D., Gergerich R.C., Martin R.R.;
RT "A virus between families: nucleotide sequence and evolution of Strawberry
RT latent ringspot virus.";
RL Virus Res. 121:199-204(2006).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY860978; AAW63128.1; -; Genomic_RNA.
DR RefSeq; YP_227367.1; NC_006964.1.
DR GeneID; 5075767; -.
DR KEGG; vg:5075767; -.
DR Proteomes; UP000204336; Genome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR Gene3D; 1.20.960.20; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR000605; Helicase_SF3_ssDNA/RNA_vir.
DR InterPro; IPR014759; Helicase_SF3_ssRNA_vir.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR Pfam; PF00680; RdRP_1; 1.
DR Pfam; PF00910; RNA_helicase; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50507; RDRP_SSRNA_POS; 1.
DR PROSITE; PS51218; SF3_HELICASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT TRANSMEM 564..583
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 595..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 858..1027
FT /note="SF3 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51218"
FT DOMAIN 1826..1948
FT /note="RdRp catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50507"
SQ SEQUENCE 2227 AA; 249903 MW; 1ECC7A766CCDE28A CRC64;
MGYSRGSRGG ADKPKLCGIC FASFPDAQER KCHYRKYNCR DSGGQLGGLV STGRCASAKE
RNLKVEADRK ELESSCDDFL TEQDMEMTFM SDLFEFTEGF SGDPITLCFA HHITYGPGDS
YISRPIYQAP GLDVADYAAF QNEKVKGTQR EFLTTDRKYD AEVLTSVVRT AIVGGGFGSP
TFDYTGLGGD GLKYRFDSDD LWSDHSKGLG RFVSAGFTES TKGSLDLKLT LQDVDEMTQA
LSDEWAEWVY FEEDLEEYLE EYLNSKIALA QEIRALKQKR TVALAQKAYD QAKEKPAVER
PISPDTVLQS ANSYLSGTKW CYDSEDEDYL PVAPLDKFHN KKHDIDFVDC CDTEYQIQPS
GTIYTETWFI DGCLPGCWFK RGVAIDEAVV CEKLPLIGKT PLELMIQYQV EPTGDLLLDI
QRALFAYYEK EALPNKKYFN LNGVPTMIVL EDWRCDLRYC LYAPFIQGDQ LKHLMVVLNA
PLPGWLVDFP KRRKSGVLQA SGWNPLRYFS KQATLGFLDG VMTKLKELIG PIINAASFVW
DLIIKAKDWA FKALEDMIEK RGEILKALLQ PLLYVCGLLL FLGSLKGLKT IVESFGIPLA
ILTGAAIGLG VYVLVTFLGQ AHMGALKRST KIWDLVQNWD KPSEVKCIDE QIIEVLVEES
PDKEEWVREL LASPHYVPEC VIDLTHMKDL LSPQKCANFK QAFEVGASEA SSPGMLFGSG
FIWKILLLLC PLSMFGVSKT LSCAKDLITI QGGQDAAGRF FQDIVGGTQE VFYTITGEKS
EFLDYIYATV GVDFQAWRAE VLELTTATPT SIFLGPQERL KRLRACKDKA DRLILQMDSR
KVPGAYITHF NSLLQSLDRA LVECQQALSV GKWRKTPACI WLYGDSHVGK SVCSQYLIDD
VLDSLDYAQT GRVFSRNGSD SFWSCYKNQS AVLYDDFGAV SEGGHFDEAE IIRLIAPAPL
PLNMPNLEAK GNTCCTSDFV FITANQAGLT PSAVIHCKKA FENRRLILAE VTAVEGGRYR
DRYRFTIHQK NEPYARDDRF QVMNYDQFMQ YVVNQSKDHF SEQVDLRDAP HTQIFAAADQ
IAAEAEEGFK TAGITIPFCM LKCIEGRMVT YYDEEKFTEM TVELSETDAD IIHSRLDPQM
ITQRLQMLLP KAAYVNLKNH FGLGTDPFEQ PNPYFNCSQR AKVIGRFLKP KVTEAQLETS
KRGFLQVTKE LAQGACRAIS DAPFLVKLLL GFGALYFVGL PILGWLKSLY SAPSLMTFAA
LGTMRASGSL SSSQDQETRR TASGRERRRY LLEASGPGAL EAKPQDVETE LASLSKHLVG
FTSIDFPDHH YRGIALGGTR VLMVYHVWLE LHSGCYKVGS LSKTFPFTVN RKNCKFQRIG
LKDLVIVDFP PTFVSFPVLK LEKWLLASHD PFMAGSGWFM EMVFQRNGVL EVAREEADYT
LLDTHDVYDA AFLKGVGLNK CVRYTICDDA GTGYRNDFFY VSQCGTPLVA NYGKGKGLKI
ASIHVVHHFS ATEKDTIIAG SGSLLTKEEY LEASLLLGDI KHPLETDRIQ ASGCLSGDEF
FDAETVFPEG LLLPSQAPRQ ATSSEIHKSS ISDGLEKLVG EKRKTEPAII SNRDTRLKDR
NLDIFKKGMM KYKAVAADMS PVTDEEEKIW NVTWDSIFDL PGGIQSKCHL LSEDENLNGV
NGDNEYRGMV VSTSEGWPEV LNRKNGEAGK ERFLLGLPGC YTLNRNLPMY QRILDLDALS
ATTIPCIVGL DTAKDERLPL SKIYQDVKTR LFTILPMEYN YLVRKYFGSF VAELMKLHNC
IPTKVGINPL GYDWTILGKK MHAKGTNWFN GDYSRFDGVT PRCLLIEISN RITKLYGDEH
RERRLHLMLA ATTRLGVAGI GLYRVSGGIP PGFALTVIVN SLVNHFLVRW SWEHMMASSS
LFFTDCVELA VVGDDNLVSV KQVAAEDFNL KKLSAFLAGF GFTLKDGSDK NKEILPEFNP
PEKCDFLKRC FKARGDRYLA PLSWLSLSES LHWVRETNMT NAAATQNNVE GFLRELFHYG
DKELYCKWRR DLISLCAENR VPHPTSYSFE ELERSWLSGK TVASIFEKEE PEIVVLKDAA
SDVAPNVHIV PAQTCLKWKP NEVPTVVWCG PNCPNQLRNA NGCFLIQAPQ GSRYPLRSTV
RNSLKRVHQR SDEVYFAGAL DQSLVHWVAA FYASMYRESF SHSKYMAAYF GDNDKGLLEA
VTAAKGW
//
