ID   Q5GL23_STRPY            Unreviewed;       425 AA.
AC   Q5GL23;
DT   01-MAR-2005, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2005, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=Collagen-like protein 1 {ECO:0000313|EMBL:AAS10186.1};
GN   Name=scl1 {ECO:0000313|EMBL:AAS10186.1};
OS   Streptococcus pyogenes.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1314 {ECO:0000313|EMBL:AAS10186.1};
RN   [1] {ECO:0000313|EMBL:AAS10186.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MGAS6274 {ECO:0000313|EMBL:AAS10186.1};
RX   PubMed=16552563; DOI=10.1007/s00253-006-0387-5;
RA   Han R., Zwiefka A., Caswell C.C., Xu Y., Keene D.R., Lukomska E., Zhao Z.,
RA   Hook M., Lukomski S.;
RT   "Assessment of prokaryotic collagen-like sequences derived from
RT   streptococcal Scl1 and Scl2 proteins as a source of recombinant GXY
RT   polymers.";
RL   Appl. Microbiol. Biotechnol. 72:109-115(2006).
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DR   EMBL; AY459361; AAS10186.1; -; Genomic_DNA.
DR   RefSeq; WP_023079691.1; NZ_WVGM01000007.1.
DR   AlphaFoldDB; Q5GL23; -.
DR   InterPro; IPR008160; Collagen.
DR   InterPro; IPR019931; LPXTG_anchor.
DR   InterPro; IPR019950; M_anchor.
DR   NCBIfam; NF038330; adhesin_SclA; 2.
DR   NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR   PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR   PANTHER; PTHR24023:SF1100; FIBRILLAR COLLAGEN NC1 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01391; Collagen; 1.
DR   Pfam; PF00746; Gram_pos_anchor; 1.
DR   PRINTS; PR00015; GPOSANCHOR.
DR   PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE   4: Predicted;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Collagen {ECO:0000313|EMBL:AAS10186.1};
KW   Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW   Secreted {ECO:0000256|ARBA:ARBA00022512}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..37
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           38..425
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004257298"
FT   DOMAIN          391..425
FT                   /note="Gram-positive cocci surface proteins LPxTG"
FT                   /evidence="ECO:0000259|PROSITE:PS50847"
FT   REGION          111..396
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        156..176
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        224..243
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        345..372
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   425 AA;  44579 MW;  6D7ABD4D01DA5040 CRC64;
     MLTSKHHNLN KLVWRYGLTS AAAVLLAFGG GASSVKAEVS TAAMTKEERQ QEIEKIKEDI
     KKEYPKASEE KFWESSFWGR RYFNEQEYLK SLQSFTEQRL QDIVNLIEKG ATKGDKGDAG
     PKGERGPAGP QGPVGPKGEA GKVGAQGPKG DPGAPGKDGA KGEKGDKGDT GERGEKGDIG
     ATGAQGPQGE KGETGAQGPA GPQGEAGKPG EQGPAGPQGE AGKPGEKAPE KSPEGEAGQP
     GEKAPEKSPE VTPTPETPEQ PGEKAPEKSP EVTPTPETPE QPGEKAPEKS PEVTPTPETP
     EQPGEKAPEK SPEVTPTPEM PEQPGEKAPE KSPEVTPTPE MPEQPGEKAP EKSKEVTPAP
     EKPADKEANQ TPERRNGNMA KTPVANNHRR LPATGEQANP FFTAAAVAVM TTAGVLAVTK
     RKENN
//