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Database: UniProt
Entry: Q5HJF7
LinkDB: Q5HJF7
Original site: Q5HJF7 
ID   Y201_STAAC              Reviewed;         252 AA.
AC   Q5HJF7;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   19-MAR-2014, entry version 80.
DE   RecName: Full=Uncharacterized response regulatory protein SACOL0201;
GN   OrderedLocusNames=SACOL0201;
OS   Staphylococcus aureus (strain COL).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcus.
OX   NCBI_TaxID=93062;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COL;
RX   PubMed=15774886; DOI=10.1128/JB.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T.,
RA   Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J.,
RA   Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S.,
RA   Haft D.H., Vamathevan J.J., Khouri H., Utterback T.R., Lee C.,
RA   Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H.,
RA   Hance I.R., Nelson K.E., Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete
RT   genome analysis of an early methicillin-resistant Staphylococcus
RT   aureus strain and a biofilm-producing methicillin-resistant
RT   Staphylococcus epidermidis strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
RN   [2]
RP   INDUCTION DURING ANAEROBIC GROWTH.
RX   PubMed=17384184; DOI=10.1128/JB.00081-07;
RA   Fuchs S., Pane-Farre J., Kohler C., Hecker M., Engelmann S.;
RT   "Anaerobic gene expression in Staphylococcus aureus.";
RL   J. Bacteriol. 189:4275-4289(2007).
CC   -!- FUNCTION: Probable member of the two-component regulatory system
CC       SACOL0202/SACOL0201.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- INDUCTION: Up-regulated during anaerobic growth.
CC   -!- PTM: Phosphorylated by SACOL0202 (Potential).
CC   -!- SIMILARITY: Contains 1 HTH araC/xylS-type DNA-binding domain.
CC   -!- SIMILARITY: Contains 1 response regulatory domain.
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DR   EMBL; CP000046; AAW37497.1; -; Genomic_DNA.
DR   RefSeq; YP_185100.1; NC_002951.2.
DR   ProteinModelPortal; Q5HJF7; -.
DR   SMR; Q5HJF7; 2-241.
DR   STRING; 93062.SACOL0201; -.
DR   EnsemblBacteria; AAW37497; AAW37497; SACOL0201.
DR   GeneID; 3236771; -.
DR   KEGG; sac:SACOL0201; -.
DR   PATRIC; 19526668; VBIStaAur112458_0200.
DR   eggNOG; COG4753; -.
DR   HOGENOM; HOG000059795; -.
DR   KO; K07720; -.
DR   OMA; DHITHIR; -.
DR   OrthoDB; EOG6G4VQG; -.
DR   ProtClustDB; CLSK884492; -.
DR   BioCyc; SAUR93062:GCEP-196-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.60; -; 2.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR009057; Homeodomain-like.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   Pfam; PF12833; HTH_18; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome; Cytoplasm; DNA-binding; Phosphoprotein;
KW   Transcription; Transcription regulation;
KW   Two-component regulatory system.
FT   CHAIN         1    252       Uncharacterized response regulatory
FT                                protein SACOL0201.
FT                                /FTId=PRO_0000299109.
FT   DOMAIN        3    118       Response regulatory.
FT   DOMAIN      153    250       HTH araC/xylS-type.
FT   DNA_BIND    170    191       H-T-H motif (By similarity).
FT   DNA_BIND    217    240       H-T-H motif (By similarity).
FT   MOD_RES      55     55       4-aspartylphosphate (By similarity).
SQ   SEQUENCE   252 AA;  29599 MW;  F42C8E41A0CE4082 CRC64;
     MFKVVICDDE RIIREGLKQI IPWGDYHFNT IYTAKDGVEA LSLIQQHQPE LVITDIRMPR
     KNGVDLLNDI AHLDCNVIIL SSYDDFEYMK AGIQHHVLDY LLKPVDHAQL EVILGRLVRT
     LLEQQSQNGR SLASCHDAFQ PLLKVEYDDY YVNQIVDQIK QSYQTKVTVS DLIQHIDVSE
     SYAMRTFKDH VGITIVDYLN RYRILQSLQL LDRHYKHYEI ADKVGFSEYK MFSYHFKKYL
     QMSPSDYCKQ AK
//
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