ID Q5HZQ7_XENLA Unreviewed; 118 AA.
AC Q5HZQ7;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=Small nuclear ribonucleoprotein Sm D2 {ECO:0000256|RuleBase:RU365051};
DE Short=Sm-D2 {ECO:0000256|RuleBase:RU365051};
DE AltName: Full=snRNP core protein D2 {ECO:0000256|RuleBase:RU365051};
GN Name=snrpd2.L {ECO:0000313|RefSeq:NP_001167498.1,
GN ECO:0000313|Xenbase:XB-GENE-964252};
GN Synonyms=sm-d2 {ECO:0000313|RefSeq:NP_001167498.1}, smd2
GN {ECO:0000313|RefSeq:NP_001167498.1}, snrpd1
GN {ECO:0000313|RefSeq:NP_001167498.1}, snrpd2
GN {ECO:0000313|RefSeq:NP_001167498.1,
GN ECO:0000313|Xenbase:XB-GENE-964252};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH88924.1};
RN [1] {ECO:0000313|RefSeq:NP_001167498.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH88924.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Egg {ECO:0000313|EMBL:AAH88924.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001167498.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU365051}.
CC -!- SIMILARITY: Belongs to the snRNP core protein family.
CC {ECO:0000256|ARBA:ARBA00008146, ECO:0000256|RuleBase:RU365051}.
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DR EMBL; BC088924; AAH88924.1; -; mRNA.
DR RefSeq; NP_001167498.1; NM_001174027.1.
DR DNASU; 100381103; -.
DR GeneID; 100381103; -.
DR KEGG; xla:100381103; -.
DR AGR; Xenbase:XB-GENE-964252; -.
DR CTD; 100381103; -.
DR Xenbase; XB-GENE-964252; snrpd2.L.
DR OrthoDB; 5485754at2759; -.
DR Proteomes; UP000186698; Chromosome 8L.
DR Bgee; 100381103; Expressed in gastrula and 19 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030532; C:small nuclear ribonucleoprotein complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd01720; Sm_D2; 1.
DR Gene3D; 2.30.30.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR047575; Sm.
DR InterPro; IPR027248; Sm_D2.
DR InterPro; IPR001163; Sm_dom_euk/arc.
DR PANTHER; PTHR12777; SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2; 1.
DR PANTHER; PTHR12777:SF0; SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2; 1.
DR Pfam; PF01423; LSM; 1.
DR SMART; SM00651; Sm; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS52002; SM; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664,
KW ECO:0000256|RuleBase:RU365051};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187,
KW ECO:0000256|RuleBase:RU365051};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365051};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU365051}.
FT DOMAIN 29..115
FT /note="Sm"
FT /evidence="ECO:0000259|PROSITE:PS52002"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 118 AA; 13541 MW; 2986059FA7E15028 CRC64;
MSLLNKPKTE MTPEELQKRE EEEFNTGPLS VLTQSVKNNT QVLINCRNNK KLLGRVKAFD
RHCNMVLENV KEMWTEVPKS GKGKKKSKPV NKDRYISKMF LRGDSVIVVL RNPLLAGK
//
