ID   Q5INB5_SHIDY            Unreviewed;       215 AA.
AC   Q5INB5;
DT   15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2005, sequence version 1.
DT   13-SEP-2023, entry version 63.
DE   SubName: Full=Beta-glucuronidase {ECO:0000313|EMBL:AAV83850.1};
DE   Flags: Fragment;
GN   Name=uidA {ECO:0000313|EMBL:AAV83850.1};
OS   Shigella dysenteriae.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=622 {ECO:0000313|EMBL:AAV83850.1};
RN   [1] {ECO:0000313|EMBL:AAV83850.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=225-75 {ECO:0000313|EMBL:AAV83849.1}, and 3341-55
RC   {ECO:0000313|EMBL:AAV83850.1};
RA   Bumbaugh A.C., Hyma K.E., Lacher D.W., Large T.M., Ouellette L.M.,
RA   Tarr C.L., Strockbine N.A., Talukder K.A., Sack D.A., Whittam T.S.;
RT   "Sequence polymorphisms and evolutionary relationships of enteroinvasive
RT   Escherichia coli and Shigella.";
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401}.
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DR   EMBL; AY698426; AAV83849.1; -; Genomic_DNA.
DR   EMBL; AY698427; AAV83850.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q5INB5; -.
DR   CAZy; GH2; Glycoside Hydrolase Family 2.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR006103; Glyco_hydro_2_cat.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR10066; BETA-GLUCURONIDASE; 1.
DR   PANTHER; PTHR10066:SF67; BETA-GLUCURONIDASE; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02836; Glyco_hydro_2_C; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          2..86
FT                   /note="Glycosyl hydrolases family 2 sugar binding"
FT                   /evidence="ECO:0000259|Pfam:PF02837"
FT   DOMAIN          90..178
FT                   /note="Glycoside hydrolase family 2 immunoglobulin-like
FT                   beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF00703"
FT   DOMAIN          180..214
FT                   /note="Glycoside hydrolase family 2 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF02836"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAV83850.1"
FT   NON_TER         215
FT                   /evidence="ECO:0000313|EMBL:AAV83850.1"
SQ   SEQUENCE   215 AA;  24067 MW;  6FAD0BB910E6256F CRC64;
     GKVWVNNQEV MEHQGGYTPF EADVTPYVIA GKSVRITVCV NNELNWQTIP PGMVITDENG
     KKKQSYFHDF FNYAGIHRSV MVYTTPNAWV DDITVVTHVA QDCNHASVDW QVVANGDVSV
     ELRDADQQVV ATGQGTSGTL QVVNPHLWQP GEGYLYELCV TAKSQTECDI YPLRVGIRSV
     AVKDEQFLIN HKPFYFTGFG RHEDADLRGK GFDNV
//