ID   Q5ISY1_ECOLX            Unreviewed;       403 AA.
AC   Q5ISY1;
DT   15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2005, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=WbuB {ECO:0000313|EMBL:AAV74538.1};
GN   Name=wbuB {ECO:0000313|EMBL:AAV74538.1};
OS   Escherichia coli.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562 {ECO:0000313|EMBL:AAV74538.1};
RN   [1] {ECO:0000313|EMBL:AAV74538.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=15629947; DOI=10.1128/JB.187.2.758-764.2005;
RA   Feng L., Senchenkova S.N., Tao J., Shashkov A.S., Liu B., Shevelev S.D.,
RA   Reeves P.R., Xu J., Knirel Y.A., Wang L.;
RT   "Structural and genetic characterization of enterohemorrhagic Escherichia
RT   coli O145 O antigen and development of an O145 serogroup-specific PCR
RT   assay.";
RL   J. Bacteriol. 187:758-764(2005).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY647260; AAV74538.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q5ISY1; -.
DR   CAZy; GT4; Glycosyltransferase Family 4.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR   CDD; cd03794; GT4_WbuB-like; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR028098; Glyco_trans_4-like_N.
DR   PANTHER; PTHR45947; SULFOQUINOVOSYL TRANSFERASE SQD2; 1.
DR   PANTHER; PTHR45947:SF3; SULFOQUINOVOSYL TRANSFERASE SQD2; 1.
DR   Pfam; PF13439; Glyco_transf_4; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   4: Predicted;
KW   Lipopolysaccharide biosynthesis {ECO:0000256|ARBA:ARBA00022985}.
FT   DOMAIN          20..175
FT                   /note="Glycosyltransferase subfamily 4-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13439"
FT   DOMAIN          210..374
FT                   /note="Glycosyl transferase family 1"
FT                   /evidence="ECO:0000259|Pfam:PF00534"
SQ   SEQUENCE   403 AA;  45802 MW;  55626CCAA6F674B9 CRC64;
     MKLALIIDDY LPNSTRVGAK MFHELAQEFI QRGHDVTVIT PGTGMQEEIS FDTFQGVKTW
     RFKSGPLKDV SKIQRVVNET LLSYRAWKAI KKWVKKETFE GVIYYSPSIF WGYLVKKIKA
     RCQCPAYLIL RDMFPQWVID AGILNAGSPI ERYFRLFEKI SCRQANRIGL MSDKNLDVFR
     KDNKGYPCEV LRNWASLTPT IIPKDYIPLR KRLGLEDKTI FFYGGNIGHA QDMTNLMRLV
     RNMAAYPQAH FLFIGQGDEV ELINSLASEW ALTNFTYLPS VNQDEFKFIL SEMDIGLFSL
     SARHSSHNFP GKLLGYMVQS LPILGSVNAG NDLLDIVNQN NAGLIHVNGE DDKLCQSALL
     MLHDIDVRRQ LGSGANILLK EQFSVESAAQ TIEMRLEACN AIN
//