ID Q5JDP8_THEKO Unreviewed; 448 AA.
AC Q5JDP8;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN OrderedLocusNames=TK1932 {ECO:0000313|EMBL:BAD86121.1};
OS Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS (Pyrococcus kodakaraensis (strain KOD1)).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=69014 {ECO:0000313|EMBL:BAD86121.1, ECO:0000313|Proteomes:UP000000536};
RN [1] {ECO:0000313|EMBL:BAD86121.1, ECO:0000313|Proteomes:UP000000536}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-918 / JCM 12380 / KOD1
RC {ECO:0000313|Proteomes:UP000000536};
RX PubMed=15710748; DOI=10.1101/gr.3003105;
RA Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL Genome Res. 15:352-363(2005).
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DR EMBL; AP006878; BAD86121.1; -; Genomic_DNA.
DR RefSeq; WP_011250882.1; NC_006624.1.
DR AlphaFoldDB; Q5JDP8; -.
DR STRING; 69014.TK1932; -.
DR EnsemblBacteria; BAD86121; BAD86121; TK1932.
DR GeneID; 78448463; -.
DR KEGG; tko:TK1932; -.
DR PATRIC; fig|69014.16.peg.1888; -.
DR eggNOG; arCOG01174; Archaea.
DR HOGENOM; CLU_023669_4_1_2; -.
DR InParanoid; Q5JDP8; -.
DR OrthoDB; 27015at2157; -.
DR PhylomeDB; Q5JDP8; -.
DR Proteomes; UP000000536; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR030665; KaiC.
DR InterPro; IPR014774; KaiC-like_dom.
DR InterPro; IPR010624; KaiC_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR PANTHER; PTHR43637:SF1; UPF0273 PROTEIN MJ1359; 1.
DR PANTHER; PTHR43637; UPF0273 PROTEIN TM_0370; 1.
DR Pfam; PF06745; ATPase; 2.
DR PIRSF; PIRSF039117; KaiC; 1.
DR PRINTS; PR01874; DNAREPAIRADA.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51146; KAIC; 2.
DR PROSITE; PS50162; RECA_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000000536};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 2..234
FT /note="KaiC"
FT /evidence="ECO:0000259|PROSITE:PS51146"
FT DOMAIN 234..387
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT DOMAIN 236..448
FT /note="KaiC"
FT /evidence="ECO:0000259|PROSITE:PS51146"
SQ SEQUENCE 448 AA; 49938 MW; 3B8D3821CE405A91 CRC64;
MELIPTGIPS LDKALNGGFS RGSTILLAGN PGSGKTHLAI HVLYNNMRRG LKGVYVSFAE
TKKQFYRNAL QSGIDLSKME GVNLFRFYDM LTVPKDELEG MIAFLIDDIV EFKPDIIVFD
SVTVFGQMFG EEYLRSFLHS IIGRLVNAFD ALAILIDEIP YGEKRVGFGL EEFVVDGVIV
LELERMGEVI RRYLTIPKMR GRPLKRAAYE YVITDRGLEV LAIPELEFTE SEAPKSRLKT
GILGLDELLG GGLYEGSITL IAGPTGSGKT ILALNLASNL SKSGKKVLYI AYEESLAALR
DTLEKLGLEE NFRIVSMVPE GRTPVEYYAL IKDLIEKEGF DVLVIDSLSA MESHMDEKEF
IKAVRYLQLL TKEKGVTFVL TYITGSTYKL ATTGFSTLVD NLIFLTYDVP ERVGESLKRH
ILVLKARRSR NDPTLKDFTI GEGGIRIE
//
