ID Q5K3Q0_CUPSA Unreviewed; 211 AA.
AC Q5K3Q0;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE SubName: Full=Pairberry {ECO:0000313|EMBL:CAG30843.1};
DE Flags: Fragment;
GN Name=pby-1 {ECO:0000313|EMBL:CAG30843.1};
OS Cupiennius salei (American wandering spider).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC Araneomorphae; Entelegynae; Lycosoidea; Ctenidae; Cupiennius.
OX NCBI_TaxID=6928 {ECO:0000313|EMBL:CAG30843.1};
RN [1] {ECO:0000313|EMBL:CAG30843.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15733314; DOI=10.1111/j.1525-142X.2005.05018.x;
RA Schoppmeier M., Damen W.G.M.;
RT "Expression of Pax group III genes suggests a single-segmental periodicity
RT for opisthosomal segment patterning in the spider Cupiennius salei.";
RL Evol. Dev. 7:160-169(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the paired homeobox family.
CC {ECO:0000256|ARBA:ARBA00005733}.
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DR EMBL; AJ744784; CAG30843.1; -; mRNA.
DR AlphaFoldDB; Q5K3Q0; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR043182; PAIRED_DNA-bd_dom.
DR InterPro; IPR001523; Paired_dom.
DR InterPro; IPR043565; PAX_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR45636; PAIRED BOX PROTEIN PAX-6-RELATED-RELATED; 1.
DR PANTHER; PTHR45636:SF38; PROTEIN GOOSEBERRY-RELATED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF00292; PAX; 1.
DR PRINTS; PR00027; PAIREDBOX.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00351; PAX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS00034; PAIRED_1; 1.
DR PROSITE; PS51057; PAIRED_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682}; Paired box {ECO:0000256|ARBA:ARBA00022724};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..112
FT /note="Paired"
FT /evidence="ECO:0000259|PROSITE:PS51057"
FT DOMAIN 162..211
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT REGION 104..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAG30843.1"
FT NON_TER 211
FT /evidence="ECO:0000313|EMBL:CAG30843.1"
SQ SEQUENCE 211 AA; 23430 MW; BF6B0407C2828B55 CRC64;
RPLPNHIRLK IVELAAAGVR PCVISRKLRV SHGCVSKILN RYQETGSIRP GVIGGSKPRV
ATPEVEKKIE EYKRDSPGIF SWEIRDRLIK EGICDKSTAP SVSSISRVLR GSRAGSRSGD
SGSDSADGSS RKADHSIDEI LGGGTNDIDS DCDSEPGIPL KRKQRRSRTT FSAEQLELLE
KAFERTQYPD VYTREELAQR TKLTEARIQV W
//
