ID Q5K5S8_ECOLX Unreviewed; 1055 AA.
AC Q5K5S8;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Antigen 43 {ECO:0000313|EMBL:CAI43838.1};
GN Name=flu {ECO:0000313|EMBL:CAI43838.1};
OS Escherichia coli.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562 {ECO:0000313|EMBL:CAI43838.1};
RN [1] {ECO:0000313|EMBL:CAI43838.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RW1374 {ECO:0000313|EMBL:CAI43838.1};
RX PubMed=11682182; DOI=10.1111/j.1574-6968.2001.tb10866.x;
RA Jores J., Rumer L., Kiessling S., Kaper J.B., Wieler L.H.;
RT "Identification of a new pathogenicity island inserted in the pheV tRNA
RT gene of the bovine Shiga toxin-producing E. coli strain RW1374 (O103:H2)
RT harboring a locus of enterocyte effacement that is flanked by intact
RT insertion elements.";
RL FEMS Microbiol. Lett. 204:75-79(2001).
RN [2] {ECO:0000313|EMBL:CAI43838.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RW1374 {ECO:0000313|EMBL:CAI43838.1};
RX PubMed=12635929; DOI=10.1078/1438-4221-00229;
RA Rumer L., Jores J., Kirsch P., Cavignac Y., Zehmke K., Wieler L.H.;
RT "Dissemination of pheU- and pheV-located genomic islands among
RT enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli and their
RT possible role in the horizontal transfer of the locus of enterocyte
RT effacement (LEE).";
RL Int. J. Med. Microbiol. 292:463-475(2003).
RN [3] {ECO:0000313|EMBL:CAI43838.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RW1374 {ECO:0000313|EMBL:CAI43838.1};
RX PubMed=15715170; DOI=10.1016/j.ijmm.2004.09.009;
RA Jores J., Wagner S.K., Rumer L., Eichberg J., Laturnus C., Kirsch P.,
RA Schierack P., Tschaepe H., Wieler L.H.;
RT "Description of a 111-kb pathogenicity island (PAI) encoding various
RT virulence features in the enterohemorrhagic E. coli (EHEC) strain RW1374
RT (O103:H2) and detection of a similar PAI in other EHEC strains of serotype
RT 0103:H2.";
RL Int. J. Med. Microbiol. 294:417-425(2005).
CC -!- SUBCELLULAR LOCATION: Cell surface {ECO:0000256|ARBA:ARBA00004241}.
CC Periplasm {ECO:0000256|ARBA:ARBA00004418}.
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DR EMBL; AJ303141; CAI43838.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5K5S8; -.
DR GO; GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR CDD; cd01344; PL2_Passenger_AT; 1.
DR Gene3D; 2.160.20.20; -; 1.
DR Gene3D; 2.40.128.130; Autotransporter beta-domain; 1.
DR InterPro; IPR043990; AC_1.
DR InterPro; IPR030930; AIDA.
DR InterPro; IPR005546; Autotransporte_beta.
DR InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR InterPro; IPR012332; Autotransporter_pectin_lyase_C.
DR InterPro; IPR024973; ESPR.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR NCBIfam; NF033177; auto_Ag43; 1.
DR NCBIfam; TIGR04415; O_hepto_targRPT; 7.
DR PANTHER; PTHR12338:SF9; ANTIGEN 43; 1.
DR PANTHER; PTHR12338; AUTOTRANSPORTER; 1.
DR Pfam; PF18883; AC_1; 1.
DR Pfam; PF16168; AIDA; 2.
DR Pfam; PF03797; Autotransporter; 1.
DR Pfam; PF13018; ESPR; 1.
DR SMART; SM00869; Autotransporter; 1.
DR SUPFAM; SSF103515; Autotransporter; 1.
DR SUPFAM; SSF51126; Pectin lyase-like; 2.
DR PROSITE; PS51208; AUTOTRANSPORTER; 1.
PE 4: Predicted;
KW Dioxygenase {ECO:0000313|EMBL:CAI43838.1};
KW Isomerase {ECO:0000313|EMBL:CAI43838.1};
KW Oxidoreductase {ECO:0000313|EMBL:CAI43838.1};
KW Periplasm {ECO:0000256|ARBA:ARBA00022764}.
FT DOMAIN 762..1055
FT /note="Autotransporter"
FT /evidence="ECO:0000259|PROSITE:PS51208"
SQ SEQUENCE 1055 AA; 108849 MW; 6F427D392CC56311 CRC64;
MLFCTCRYPH LWVPAFLFTL CKEKLMKRHL NTSYRLVWNH ITGTLVVASE LARSRGKRAG
VAVALSLAAV TSVPALAADT VVQAGETVND GTLTNHDNQI VFGTANGMTI STGLEYGPDN
EANTGGQWIQ NGGTANNTTV TGGGLQRVNP GGSVSDTVIS AGGGQSLQGQ AVNTTLNGGE
QWVHEDGIAT GTVINEKGWQ AIKSGAVATD TVVNTGAEGG PDAENGDTGQ TVYGDAVRTT
INKNGRQIVA AEGTANTTVV YAGGDQTVHG HALDTTLNGG YQYVHNGGTA SGTVVNSDGW
QIVKNGGVAG NTTVNQKGRL QVDAGGTATN VTLKQGGALV TSTAATVTGI NRLGAFSVVE
GKADNVVLEN GGRLDVLTGH TATNTRVDDG GTLDVRNGGT ATTVSMGNGG VLLADSGAAV
SGTRSDGKAF SIGGGQADAL MLEKGSSFTL NAGDTATDTT VNGGLFTARG GTLAGTTTLN
NGAILTLSGK TVNNDTLTIR EGDALLQGGS LTGNGSVEKS GSGTLTVSNT TLTQKAVNLN
EGTLTLNDST VTTDVIAQRG TALKLTGSTV LNGAIDPTNV TLASGATWNI PDNATVQSVV
DDLSHAGQIH FTSTRTGKFV PATLKVKNLN GQNGTISLRV RPDMAQNNAD RLVIDGGRAT
GKTILNLVNA GNSASGMATT GKGIQVVEAI NGATTEEGAF VQGNKLQAGA FNYSLNRDSD
ESWYLRSENA YRAEVPLYAS MLTQAMDYDR ILAGSRSHQT GVNGENNSVR LSIQGGHLGH
DNNGGIARGA TPESSGSYGF VRLEGDLLRT EVAGMSVTAG VYGAAGHSSV DVKDDDGSRA
GTVRDDAGSL GGYLNLIHNA SGLWADIVAQ GTRHSMKASS DNNDFRARGW GWLGSLETGL
PFSITDNLML EPQLQYTWQG LSLDDGKDNA GYVKFGHGSA QHVRAGFRLG SHNDMTFGEG
TSSRDTLRGS AKHSVRELPV NWWVQPSVIR TFSSRGDMSM GTAAAGSNMT FSPSQNGTSL
DWKPVSGKIS PWAFRQVMST ASAAAALKAI TVRPR
//
