ID Q5K9I4_CRYNJ Unreviewed; 571 AA.
AC Q5K9I4; Q55K14;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 08-NOV-2023, entry version 91.
DE RecName: Full=Ricin B lectin domain-containing protein {ECO:0000259|SMART:SM00458};
GN OrderedLocusNames=CNK01820 {ECO:0000313|EMBL:AAW46144.1};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW46144.1, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW46144.1, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
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DR EMBL; AE017351; AAW46144.1; -; Genomic_DNA.
DR RefSeq; XP_567661.1; XM_567661.1.
DR AlphaFoldDB; Q5K9I4; -.
DR CAZy; CBM13; Carbohydrate-Binding Module Family 13.
DR PaxDb; 214684-Q5K9I4; -.
DR EnsemblFungi; AAW46144; AAW46144; CNK01820.
DR VEuPathDB; FungiDB:CNK01820; -.
DR eggNOG; ENOG502SS8S; Eukaryota.
DR HOGENOM; CLU_477349_0_0_1; -.
DR InParanoid; Q5K9I4; -.
DR OrthoDB; 1447990at2759; -.
DR Proteomes; UP000002149; Chromosome 11.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR024653; Peptidase_M10/M27/M57.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR Pfam; PF12388; Peptidase_M57; 1.
DR Pfam; PF00652; Ricin_B_lectin; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002149};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..571
FT /note="Ricin B lectin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012655428"
FT DOMAIN 30..165
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|SMART:SM00458"
FT REGION 162..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 571 AA; 61880 MW; B610477B8CC5DE1C CRC64;
MHIAYILGLV PLAFAGVIKH DPPKFQPIQS TRIVRLHPNG DKSKCVDLLG NTRQDGQPVQ
ICDCDGTPAQ DWVLNAGRGQ TKVQLAGTSF CLDATHPYAA DGTNMKIWKC LDVQQQDWYW
TSDNRIVLRD QGKCLDWATG DRSDFNQLQV WRCSTDNNNQ VWTTGPDYGG NHGGDAGGNP
GGNQGDDSRG KTNTGGNPGG NQGGDSGGKT NHIIPDPPGP DPNSEPLNPA LEAIVNVTEA
AGPWPPMINF DGDYSNDDVT VSDQVPFDYC IGEGSGNPTD DEGQQQGQNF TANVAGIGRD
FCLDNFGNPD IRNTISFDNN TSIGNGADTG RALHKRTFAD SGATGTPNRW RRGSVISICV
ERNNNYLVPY ASSPVPIRAS AIVASAMVRA INFWNAGLNK RFVSFEFVEN CNDAVFHTLA
VDQIKSAKEP TVLATAPFPP RGEEGARNRN IFVWNTAFEA NFQNVLTFIM SHELGHTLGL
AHEDCKSRDQ PCEVITDKVA GSVVESRISG STTQLFNGPT PLDIAGANEY YSLAAGPNTP
ENIVLWPATR GPFINYPPLP KCKWFLGICY Y
//
