ID Q5KA22_CRYNJ Unreviewed; 550 AA.
AC Q5KA22; Q55LH4;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 24-JAN-2024, entry version 80.
DE SubName: Full=Expressed protein {ECO:0000313|EMBL:AAW45896.1};
GN OrderedLocusNames=CNJ03340 {ECO:0000313|EMBL:AAW45896.1};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW45896.1, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW45896.1, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
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DR EMBL; AE017350; AAW45896.1; -; Genomic_DNA.
DR RefSeq; XP_567413.1; XM_567413.1.
DR AlphaFoldDB; Q5KA22; -.
DR STRING; 214684.Q5KA22; -.
DR PaxDb; 214684-Q5KA22; -.
DR EnsemblFungi; AAW45896; AAW45896; CNJ03340.
DR GeneID; 3254362; -.
DR KEGG; cne:CNJ03340; -.
DR VEuPathDB; FungiDB:CNJ03340; -.
DR eggNOG; ENOG502RZXZ; Eukaryota.
DR HOGENOM; CLU_022899_2_0_1; -.
DR InParanoid; Q5KA22; -.
DR OMA; QRLVILW; -.
DR OrthoDB; 2078816at2759; -.
DR Proteomes; UP000002149; Chromosome 10.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR010640; Low_temperature_requirement_A.
DR PANTHER; PTHR36840; BLL5714 PROTEIN; 1.
DR PANTHER; PTHR36840:SF1; BLL5714 PROTEIN; 1.
DR Pfam; PF06772; LtrA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002149};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 138..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..514
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 528..550
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 550 AA; 61912 MW; 801DFAD31EF36602 CRC64;
MTEHRRPSPP ATSVPQRHHS VKGLQRRGTY GTENHLVFHE DFQEEWKPLR VRELIRPLTV
RQWIEGGKIH REPISRETPR FELFFDLLFV AIIHQLADAA IEEPGGRSVA RFILTFWPSW
SVWEEARKFA NQSGTDDLLH RLWILIGMMT LIGYTANASA IELEPTGEEE TVDHSAVRAA
VAFWLVIKLT RVIVLLYYAW KLPSFRNAHL WKAVAVLIPM FFLLPLIWVT SRPAQIVLAT
LLIVVDVCRI DLLVLAIRGQ IYEFQQRRAQ GKKGLGVKGW HRMPDLPQAY KVPVTNIEHA
VERLGAFVVI VLGEMVMNLV YTAVKGEIGV SRQYGKAALG LMVAWAINYL YMLPSEPSAE
YEHALRHSWF SGICFTFFHW PLCAALILAS AASGKMVAND EVEIGVHWYW GSGVGFAIIF
MAILDLTHQD LAPGQARIPR VIRALLALCA GLSLILFSLG TQHMPSTGVL AITVGITWFL
LAFNVFGMLP KPGTVQKEEL ERRERQEEQG RGVVVQDLDG RAELESGGGV GKQREERVEE
GRLEEGGSRG
//
