ID Q5KA52_CRYNJ Unreviewed; 385 AA.
AC Q5KA52; Q55LD6;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE RecName: Full=GH16 domain-containing protein {ECO:0000259|PROSITE:PS51762};
GN OrderedLocusNames=CNJ03040 {ECO:0000313|EMBL:AAW46065.1};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW46065.1, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW46065.1, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE017350; AAW46065.1; -; Genomic_DNA.
DR RefSeq; XP_567582.1; XM_567582.1.
DR AlphaFoldDB; Q5KA52; -.
DR STRING; 214684.Q5KA52; -.
DR CAZy; GH16; Glycoside Hydrolase Family 16.
DR PaxDb; 214684-Q5KA52; -.
DR EnsemblFungi; AAW46065; AAW46065; CNJ03040.
DR GeneID; 3254038; -.
DR KEGG; cne:CNJ03040; -.
DR VEuPathDB; FungiDB:CNJ03040; -.
DR eggNOG; ENOG502SIEA; Eukaryota.
DR HOGENOM; CLU_016972_2_1_1; -.
DR InParanoid; Q5KA52; -.
DR OMA; WAMQLET; -.
DR OrthoDB; 1932445at2759; -.
DR Proteomes; UP000002149; Chromosome 10.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0009251; P:glucan catabolic process; IBA:GO_Central.
DR CDD; cd02181; GH16_fungal_Lam16A_glucanase; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000757; GH16.
DR PANTHER; PTHR10963:SF24; GLYCOSIDASE C21B10.07-RELATED; 1.
DR PANTHER; PTHR10963; GLYCOSYL HYDROLASE-RELATED; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51762; GH16_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002149};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..385
FT /note="GH16 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004258153"
FT DOMAIN 15..283
FT /note="GH16"
FT /evidence="ECO:0000259|PROSITE:PS51762"
SQ SEQUENCE 385 AA; 40151 MW; 958753791305D737 CRC64;
MLKLALATAA TIASIQVSAT TYPLSDSFSG TSFFDGFRFP AETYDNTTNG DVFWATADNT
SLLYVNDNDR VIIKVDNESD VVYLQKRYAP KLLSQKTWDI GTVWVMDAVH MPYGCSVWPA
FWTQGPNWPA GGEIDISEGI NLRTNNMVAL HTTGGTCTIS NSSSMSGSIT YDNCDISQNS
DSGCTVNDTN TDSYGAGFAA AGGGVFVAEW ATDGIRVWFL TRDAVPDSLS VSASSIDTST
LGEPVALYSS ETCDVQNLFG PQTLTIDITL CGDFAGNADL LAQTCGALVG DNTCYTTYVV
NNQTSNLAQA YYEINYINVY SSNSSSNASA TSTASAGVST SATSGSGSTA SANASASGSS
SGAGRVEAVL GGLLGALLFG LAMIL
//
