ID Q5KGL5_CRYNJ Unreviewed; 355 AA.
AC Q5KGL5;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 2.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=Solute carrier family 39 (Zinc transporter), member 9 {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=CNE03190 {ECO:0000313|EMBL:AAW43568.2};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW43568.2, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW43568.2, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE017345; AAW43568.2; -; Genomic_DNA.
DR RefSeq; XP_570875.1; XM_570875.1.
DR AlphaFoldDB; Q5KGL5; -.
DR STRING; 214684.Q5KGL5; -.
DR PaxDb; 214684-Q5KGL5; -.
DR EnsemblFungi; AAW43568; AAW43568; CNE03190.
DR VEuPathDB; FungiDB:CNE03190; -.
DR eggNOG; KOG3907; Eukaryota.
DR HOGENOM; CLU_700235_0_0_1; -.
DR InParanoid; Q5KGL5; -.
DR OrthoDB; 1384563at2759; -.
DR Proteomes; UP000002149; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006829; P:zinc ion transport; IEA:InterPro.
DR InterPro; IPR003689; ZIP.
DR InterPro; IPR045891; ZIP9.
DR PANTHER; PTHR16133; SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED; 1.
DR PANTHER; PTHR16133:SF0; ZINC_IRON REGULATED TRANSPORTER-RELATED PROTEIN 102B, ISOFORM E; 1.
DR Pfam; PF02535; Zip; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002149};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 106..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 355 AA; 36708 MW; 83E1EDC1E08A36C7 CRC64;
MPIVLLLLQS AAMFAASFLV GILPLSFKSA TSGRTLKAIS VTGMGLLVGA ALTIIIPEGV
ATLYSAMPQD GKDHDEKAIH AIGLGLLSGF SLMLLIESLI PHESHQSQPS SSYASPSPPG
SPLSIESSSR PPPQHINSNT PIVSKPKRMS VDDSESEAAT RMSTIHGLNA TLGLVIHGAA
DGIALGASSL ASGSRSLSLI IFLAVLVHKG PTALGLTTTL LSLGLPISSI RQRLIIFSFA
APVGAILTFI LVSAFGTSKV GGANAGGDAL GWWTGVALLF SGGSFLYVAT VIQPLSSHTD
AHSHPQQSHH LESGHGPEDH ADPQDRPLGT YQRTALLVFG MGLPVILSWL VGDAH
//
