ID Q5KJT6_CRYNJ Unreviewed; 358 AA.
AC Q5KJT6;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=Quinone oxidoreductase, putative {ECO:0000313|EMBL:AAW42436.1};
GN OrderedLocusNames=CNC05420 {ECO:0000313|EMBL:AAW42436.1};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW42436.1, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW42436.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JEC21 {ECO:0000313|EMBL:AAW42436.1};
RA Loftus B., Amedeo P., Roncaglia P., Vamathevan J., Utterback T.,
RA Van Aken S., Fraser C.;
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAW42436.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 {ECO:0000313|EMBL:AAW42436.1};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
RN [3] {ECO:0000313|EMBL:AAW42436.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JEC21 {ECO:0000313|EMBL:AAW42436.1};
RA Janbon G., Paulet D., Chon C.C., Mornico D.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AE017343; AAW42436.1; -; Genomic_DNA.
DR RefSeq; XP_569743.1; XM_569743.1.
DR AlphaFoldDB; Q5KJT6; -.
DR STRING; 214684.Q5KJT6; -.
DR PaxDb; 214684-Q5KJT6; -.
DR EnsemblFungi; AAW42436; AAW42436; CNC05420.
DR GeneID; 3256818; -.
DR KEGG; cne:CNC05420; -.
DR VEuPathDB; FungiDB:CNC05420; -.
DR eggNOG; KOG1198; Eukaryota.
DR HOGENOM; CLU_026673_3_3_1; -.
DR InParanoid; Q5KJT6; -.
DR OMA; RERVPCT; -.
DR OrthoDB; 909506at2759; -.
DR Proteomes; UP000002149; Chromosome 3.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd05289; MDR_like_2; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR PANTHER; PTHR44013; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C; 1.
DR PANTHER; PTHR44013:SF1; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002149}.
FT DOMAIN 14..338
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 358 AA; 38064 MW; DAE638B18959A2B2 CRC64;
MSSTMKAVAY TRYGGPEVTQ IRSFSVPLPK KGEVQVRVAA GGLNPVDWHQ RGGEFKYITP
WTLPVIAGNE FSGTVTVVGD DVAKFAVGDR VVCRTTKSAM GGLGSYVVMP ASIVAKAPTT
VDLVDAAGLP LAGLTAEQAL DTLDVKSGDR ILITGGAGGV GLFAIQIAKI RGAHVTTTAS
DAGKPYVLKA GADTVIDYRN QKLAELPEKF VKVFDVAGGE EALISDVIPA VAEGGHIVSV
AGPLIPGVFD TILPAWKSLL INLVLSSRSR AVRNAAASHG VRYEYLFMRP DGVQLEHLCN
LVDEGKLVIN IDSRFKLVDF ARAFERLESG RSKGKVIIEF PDSEEEQTAV QEASERTK
//
