ID Q5KLB5_CRYNJ Unreviewed; 327 AA.
AC Q5KLB5;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Expressed protein {ECO:0000313|EMBL:AAW42054.1};
GN OrderedLocusNames=CNC00080 {ECO:0000313|EMBL:AAW42054.1};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW42054.1, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW42054.1, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
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DR EMBL; AE017343; AAW42054.1; -; Genomic_DNA.
DR RefSeq; XP_569361.1; XM_569361.1.
DR AlphaFoldDB; Q5KLB5; -.
DR PaxDb; 214684-Q5KLB5; -.
DR EnsemblFungi; AAW42054; AAW42054; CNC00080.
DR GeneID; 3256619; -.
DR VEuPathDB; FungiDB:CNC00080; -.
DR eggNOG; ENOG502SF29; Eukaryota.
DR HOGENOM; CLU_860569_0_0_1; -.
DR InParanoid; Q5KLB5; -.
DR OMA; WFISLPR; -.
DR OrthoDB; 1450039at2759; -.
DR Proteomes; UP000002149; Chromosome 3.
DR InterPro; IPR014144; LigD_PE_domain.
DR PANTHER; PTHR39465:SF1; DNA LIGASE D 3'-PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR39465; DNA LIGASE D, 3'-PHOSPHOESTERASE DOMAIN; 1.
DR Pfam; PF13298; LigD_N; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002149}.
FT DOMAIN 102..202
FT /note="DNA ligase D 3'-phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF13298"
FT REGION 1..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..77
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..226
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 327 AA; 36984 MW; 32C284B84B6C9AA1 CRC64;
MWTLHQLTEN KATRSTTGSP SRSPSPSVAR KRARLSSSSP KMAPSLVKKE VEEVSSGKPD
SSKLEEGGDE PKPDVEREWE GFSKDVLEKW PALKKRNFWC IQRHSATVVA LHYDLRMHLD
GVTVSWAIPK GLLGISKSGE ARRMAVETTL HPLWYTIHEG SDGRTFGQGR QGGTLLWDIG
EYTIDLPSGY IPDLDTDEEE EAENRRRFKK RRKDSESDGR EEEDKFRNAL HRHIGFGKSR
SMHFTLKGGK KMTNHSFILV LSSNPYKYNT VSLEGKEKKT WFISLPRGVD SYPWDQGGED
GDFYGRSIKS GMTFQQVCQG LADDSSQ
//
