ID Q5KNC5_CRYNJ Unreviewed; 812 AA.
AC Q5KNC5; Q55Z09;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 127.
DE SubName: Full=Chromatin assembly complex protein, putative {ECO:0000313|EMBL:AAW41195.1};
GN OrderedLocusNames=CNA06970 {ECO:0000313|EMBL:AAW41195.1};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW41195.1, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW41195.1, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AE017341; AAW41195.1; -; Genomic_DNA.
DR RefSeq; XP_567014.1; XM_567014.1.
DR AlphaFoldDB; Q5KNC5; -.
DR STRING; 214684.Q5KNC5; -.
DR PaxDb; 214684-Q5KNC5; -.
DR EnsemblFungi; AAW41195; AAW41195; CNA06970.
DR GeneID; 3253228; -.
DR KEGG; cne:CNA06970; -.
DR VEuPathDB; FungiDB:CNA06970; -.
DR eggNOG; KOG1009; Eukaryota.
DR HOGENOM; CLU_010127_3_0_1; -.
DR InParanoid; Q5KNC5; -.
DR OMA; CIVSNLH; -.
DR OrthoDB; 5478541at2759; -.
DR Proteomes; UP000002149; Chromosome 1.
DR GO; GO:0033186; C:CAF-1 complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0006335; P:DNA replication-dependent chromatin assembly; IEA:InterPro.
DR GO; GO:0006334; P:nucleosome assembly; IBA:GO_Central.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR045145; PTHR15271.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15271; CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; 1.
DR PANTHER; PTHR15271:SF4; CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; 1.
DR Pfam; PF00400; WD40; 4.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002149};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 113..144
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 173..214
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 35..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 254..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 450..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 732..812
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..337
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..364
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..468
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..692
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..763
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 777..812
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 812 AA; 86149 MW; 92A9937E7D5A930A CRC64;
MRPKVLEIAW HETQAVYSCD FQPLPLPQLK RLLAASTTSE SEEDRDRIEK GSSSAATAAG
GRQYRLATAG GDSKVRIWMV YPNIPSIPPS TYAALTGQEY TPHPPRVEYL ATLSKHTAPV
NVVRFSPSGQ ILASAGDDGN VILWVPSDRP SVTFGETSDD LPDKEHWRLQ KMLQVTTKHV
YDLSWSPDGE YLIAGSTDNT ATIWKAATGE CVFALREHLH NVQGVAWDPL NEYIATQSSD
RAVHVNTFTT RNGIPDVHPV SRSTRMEIRH SRTPSISSAS RPSMVRRGST TSEAGSVITT
ASDFPEAALP PHAPVLAGVS ASATPATPSA SVPSTPQVAP APMNPPATSN RPCSRRSSFS
GSQAAASPAL SAAAFSHLAR SARSPSPIPP LPAIRAPPAS TINQRLYGEE GATRFFRRLT
FSPDGSLLLT PAGQIEDQVY KGSPLLTAKN ISQDTSDPLS SSVPRPKNVE TGKPTAYIYS
RANLSRPPIA HLPGHKTSSV AIRFSPVFYD LRQNGQLSAE PKHVTFDKND TQPVHVSLNM
PPPPAPSGSR EKEKEKEGDK VLGSVFALPY RLLYAVACQD SVLLYDTQQA GPIAIFKGLH
YAGFTDVAWS PDGQCLFLSS ADGYCSIVIF DLGELGTVHP TQQHHRQLQA IAQSHNNGIS
TPLPPSLTHR DSIHSSHSQS GASATGHSPA VSHVARQSPA PGVARSDREG STASSVVGAS
GSVSASLLSV SNVGGGAKAP PSSASSVTVT DQVLPTPTPS DTEGPSAAGV DLGIAVSQEE
DAKKREGAGE TTQAEAPKKK RRVALTHLGS EQ
//
