ID Q5NKT7_PANTR Unreviewed; 772 AA.
AC Q5NKT7;
DT 01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 01-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Intercellular adhesion molecule 5 {ECO:0000313|EMBL:AAQ14922.1};
DE Flags: Fragment;
GN Name=ICAM5 {ECO:0000313|EMBL:AAQ14922.1};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:AAQ14922.1};
RN [1] {ECO:0000313|EMBL:AAQ14922.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bonnie {ECO:0000313|EMBL:AAQ14922.1};
RC TISSUE=Blood {ECO:0000313|EMBL:AAQ14922.1};
RX PubMed=15572059; DOI=10.1016/j.jtbi.2004.08.024;
RA Walter N.A.R., Stebbing J., Messier W.;
RT "The potential significance of adaptive evolution and dimerization in
RT chimpanzee intercellular cell adhesion molecules (ICAMs).";
RL J. Theor. Biol. 232:339-346(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. ICAM family.
CC {ECO:0000256|ARBA:ARBA00005925}.
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DR EMBL; AF340065; AAQ14922.1; -; mRNA.
DR AlphaFoldDB; Q5NKT7; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005178; F:integrin binding; IEA:InterPro.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003988; ICAM.
DR InterPro; IPR048679; ICAM1_3_5_D2.
DR InterPro; IPR013768; ICAM_N.
DR InterPro; IPR047012; ICAM_VCAM.
DR InterPro; IPR003987; ICAM_VCAM_N.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR13771; INTERCELLULAR ADHESION MOLECULE; 1.
DR PANTHER; PTHR13771:SF9; INTERCELLULAR ADHESION MOLECULE 5; 1.
DR Pfam; PF21146; ICAM1_3_5_D2; 1.
DR Pfam; PF03921; ICAM_N; 1.
DR PRINTS; PR01473; ICAM.
DR PRINTS; PR01472; ICAMVCAM1.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 8.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 2: Evidence at transcript level;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 381..459
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 464..541
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 639..712
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 719..772
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAQ14922.1"
FT NON_TER 772
FT /evidence="ECO:0000313|EMBL:AAQ14922.1"
SQ SEQUENCE 772 AA; 82629 MW; C77C950A4BA5DC6F CRC64;
AVSQEPFWAD LQPRVAFVER GGSLWLNCST NCPRPERGGL ETSLRRNGTQ RGLRWLARQL
VDIREPETQP VCFFRCARRT LQARGLIRTF QRPDRVELMP LPPWQPVGEN FTLSCRVPGA
GPRASLTLTL LRGAQELIRR SFAGEPPRAR GAVLTATVLA RREDHGANFS CRAELDLRPH
GLGLFENSSA PRELRTFSLS PDPPRLAAPR LLEVGSERPV SCTLDGLFPA SEARVYLALG
DQNLSPDVTL EGDAFVATAT ATASAEQEGA RQLVCNVTLG GENRETRENV TIYSFPAPLL
TLSEPSVSEG QMVTVTCSAG AQALVTLEGV PAAVPGQPAQ LQLNATENDD RRSFFCDATL
DVDGETLIKN RSAELRVLYA PRLDDSDCPR SWTWPEGPEQ TLRCEARGNP EPSVHCARSD
GGAVLALGLL GPVTRALSGT YRCKAANDQG EAVKDVTLTV EYAPALDSVG CPERITWLEG
TEASLSCVAH GVPPPDVICV RSGELGAVIE GLLRVAREHA GTYRCEATNP RGSAAKNVAV
TVEYGPRFEE PSCPSNWTWV EGSGRLFSCE VDGKPQPSVK CVGSGGATEG VLLPLAPPDP
SPRAPRIPRV LAPGIYVCNA TNRHGSVAKT VVVSAESPPE MDESTCPSHQ TWLEGAEASA
LACAARGRPS PGVRCSREGI PWPEQQRVSR EDAGTYHCVA TNAHGTDSRT VTVGVEYRPV
VAELAASPPG GVRPGGNFTL TCRAEAWPPA QISWRAPPGA LNIGLSSNNS TL
//
