ID Q5NTN4_9BACT Unreviewed; 216 AA.
AC Q5NTN4;
DT 01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 01-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Transcriptional regulator TetR family {ECO:0000313|EMBL:BAD80987.1};
GN Name=nap3-3 {ECO:0000313|EMBL:BAD80987.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:BAD80987.1};
RN [1] {ECO:0000313|EMBL:BAD80987.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15608629; DOI=10.1038/nbt1048;
RA Uchiyama T., Abe T., Ikemura T., Watanabe K.;
RT "Substrate-induced gene-expression screening of environmental metagenome
RT libraries for isolation of catabolic genes.";
RL Nat. Biotechnol. 23:88-93(2005).
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DR EMBL; AB186503; BAD80987.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5NTN4; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF164; TRANSCRIPTIONAL REPRESSOR MCE3R; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335}.
FT DOMAIN 7..67
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 30..49
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 195..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 216 AA; 24195 MW; 13A1DC1D13C97BC5 CRC64;
MAKQAPRNMR EEILDASVPL FAMYGFEGVS MRFIAAAVGV TPAALYYHFS DKEQIYLDVV
RHAFEGRIGP LKPLLDGGGE PWGRLEAFVA RLTHVLAKEE DFRRLMQWVM LDVDERRQQS
LANCVFGDLF DALCKIAGEL APNQDAHLLV ISMIALVVYP FETRPVGRFL PGYQRQQEDP
EAIARHVVGL LRNGLGASDE GKSQQRPVQG IRAEQT
//
