ID   Q5NTY2_PLABE            Unreviewed;       810 AA.
AC   Q5NTY2;
DT   01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   01-FEB-2005, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Sporozoite micronemal protein essential for cell traversal {ECO:0000313|EMBL:SCL94079.1};
DE   SubName: Full=Sporozoite protein with MACPF related domain {ECO:0000313|EMBL:BAD83404.1};
GN   Name=spect2 {ECO:0000313|EMBL:BAD83404.1};
GN   Synonyms=PLP1 {ECO:0000313|EMBL:SCL94079.1};
GN   ORFNames=PBNK65E_000222900 {ECO:0000313|EMBL:SCN25917.1},
GN   PBNK65NY_000221800 {ECO:0000313|EMBL:SCL94079.1}, PBSP11A_000221600
GN   {ECO:0000313|EMBL:SCM15938.1}, PBSP11RLL_000221700
GN   {ECO:0000313|EMBL:SCM17734.1};
OS   Plasmodium berghei.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX   NCBI_TaxID=5821 {ECO:0000313|EMBL:BAD83404.1};
RN   [1] {ECO:0000313|EMBL:BAD83404.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ANKA {ECO:0000313|EMBL:BAD83404.1};
RX   PubMed=15659064; DOI=10.1111/j.1462-5822.2004.00447.x;
RA   Ishino T., Chinzei Y., Yuda M.;
RT   "A Plasmodium sporozoite protein with a membrane attack complex domain is
RT   required for breaching the liver sinusoidal cell layer prior to hepatocyte
RT   infection.";
RL   Cell. Microbiol. 7:199-208(2005).
RN   [2] {ECO:0000313|Proteomes:UP000219860, ECO:0000313|Proteomes:UP000219974}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NK65 ny {ECO:0000313|EMBL:SCL94079.1,
RC   ECO:0000313|Proteomes:UP000516480}, NK65e
RC   {ECO:0000313|EMBL:SCN25917.1, ECO:0000313|Proteomes:UP000220214}, SP11
RC   Antwerpcl1 {ECO:0000313|EMBL:SCM15938.1,
RC   ECO:0000313|Proteomes:UP000219860}, and SP11 RLL
RC   {ECO:0000313|EMBL:SCM17734.1, ECO:0000313|Proteomes:UP000219974};
RG   Pathogen Informatics;
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AB182656; BAD83404.1; -; mRNA.
DR   EMBL; LT608146; SCL94079.1; -; Genomic_DNA.
DR   EMBL; LT608258; SCM15938.1; -; Genomic_DNA.
DR   EMBL; LT608274; SCM17734.1; -; Genomic_DNA.
DR   EMBL; LT614636; SCN25917.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q5NTY2; -.
DR   SMR; Q5NTY2; -.
DR   VEuPathDB; PlasmoDB:PBANKA_1006300; -.
DR   OMA; SPHDTMQ; -.
DR   Proteomes; UP000219860; Chromosome 10.
DR   Proteomes; UP000219974; Chromosome 10.
DR   Proteomes; UP000220214; Chromosome 10.
DR   Proteomes; UP000516480; Chromosome 10.
DR   InterPro; IPR020864; MACPF.
DR   PANTHER; PTHR19324:SF33; APEC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR19324; PERFORIN-LIKE PROTEIN 1; 1.
DR   Pfam; PF01823; MACPF; 1.
DR   SMART; SM00457; MACPF; 1.
DR   PROSITE; PS51412; MACPF_2; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          198..548
FT                   /note="MACPF"
FT                   /evidence="ECO:0000259|PROSITE:PS51412"
FT   REGION          90..142
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          166..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        97..111
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        112..142
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        171..188
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   810 AA;  90997 MW;  FF37CEFFC2AA37BD CRC64;
     MKMRNIKKSL PVLFILLCIY QQYFINSLRI SVRNNKNHRD ENKFNKNMEL GTMEKPINIL
     CNDVSCNTEN NISFVNQKKK EIDSDSDLYN MFDDDASTSA GDDEDDYDDY TDDKNAEIKD
     EEQNEHIDKI DQKKDKKRTF SINKQEEEIN ENKNKTEKFF KKYKFNDANS EGDDDESDTD
     DENLDNSTEN SYEENKNPEN VIDKHMAVFP GLYFVGIGYD ILFGNPLGET DSLSDPGYRA
     QIYLLNWEFS NHGIANDLHT LQPINAWIRK ENACSRVESI NECSSVSEYT KNLSVDVSVS
     GSYMGFGSFS ASTGYKKFIN EISKRTSKTY FIKSNCIKYT IGLPPYVPWE HTTAYMNAVN
     ILPKEFTGLD GDSECTPDVY EQKKMTKQCK NVQLWIQFFK TYGTHIIVEA QLGGKITKII
     NVSNTSVNQM KKDGVSVKAQ IQAQFGFASV GGSTSVSSDN STKNDNSSYD MSEKLVVIGG
     NPIKDVTKEE NLYEWSKTVS SNPMPIHIKL LPIYKSFDSE ELKESYEKAV LYYTRLYGSS
     PHGTIQKDEN DIIKILTAST TITKIGAPPI TAECPHNQVV LFGYVLKQNF WDNTSNLKGY
     DIEICEAGLN SCTSKQGSTN KYDVSYLYIE CGTQAMSFSD QVITASNTTY NTIKCPNDYT
     IIFGFGFSSS SGKGVSAMHT HITSCRPGMK SCSLNMGNSN DKNYMYLVCV DATIWSGINE
     LTIVAKDDFH GAVNRSKQFN DGELVLSCQE NGTILTGFTG ETHTSSPYVK SPFSKCLKSL
     KSCSVHGSGQ SIGYTNYKSL FSIILCKNGE
//