ID Q5PY75_AEDAE Unreviewed; 227 AA.
AC Q5PY75;
DT 04-JAN-2005, integrated into UniProtKB/TrEMBL.
DT 04-JAN-2005, sequence version 1.
DT 24-JAN-2024, entry version 81.
DE SubName: Full=Glutathione S-transferase theta 2 {ECO:0000313|EMBL:AAV68400.1};
DE Flags: Fragment;
GN Name=GSTt2 {ECO:0000313|EMBL:AAV68400.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:AAV68400.1};
RN [1] {ECO:0000313|EMBL:AAV68400.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15944082; DOI=10.1016/j.ibmb.2005.03.008;
RA Lumjuan N., McCarroll L., Prapanthadara L.A., Hemingway J., Ranson H.;
RT "Elevated activity of an Epsilon class glutathione transferase confers DDT
RT resistance in the dengue vector, Aedes aegypti.";
RL Insect Biochem. Mol. Biol. 35:861-871(2005).
CC -!- SIMILARITY: Belongs to the GST superfamily. Theta family.
CC {ECO:0000256|ARBA:ARBA00009899}.
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DR EMBL; AY819712; AAV68400.1; -; mRNA.
DR AlphaFoldDB; Q5PY75; -.
DR SMR; Q5PY75; -.
DR VEuPathDB; VectorBase:AAEL009016; -.
DR HOGENOM; CLU_011226_2_0_1; -.
DR GO; GO:0004364; F:glutathione transferase activity; IEA:UniProtKB-EC.
DR CDD; cd03183; GST_C_Theta; 1.
DR CDD; cd03050; GST_N_Theta; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR040079; Glutathione_S-Trfase.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR004046; GST_C.
DR InterPro; IPR040077; GST_C_Theta.
DR InterPro; IPR040075; GST_N_Theta.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43917; -; 1.
DR PANTHER; PTHR43917:SF8; GH16740P-RELATED; 1.
DR Pfam; PF00043; GST_C; 1.
DR Pfam; PF02798; GST_N; 1.
DR SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR SFLD; SFLDG00358; Main_(cytGST); 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS50405; GST_CTER; 1.
DR PROSITE; PS50404; GST_NTER; 1.
PE 2: Evidence at transcript level;
KW Transferase {ECO:0000313|EMBL:AAV68400.1}.
FT DOMAIN 5..88
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
FT DOMAIN 94..227
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
FT NON_TER 227
FT /evidence="ECO:0000313|EMBL:AAV68400.1"
SQ SEQUENCE 227 AA; 26571 MW; E561C2DDDEAD43B3 CRC64;
MANGRNIRFY YDLISQPCRA LYIFLEQNKI HYQKCPIALR KWEHTTPEYL QNVNRFGKVP
AIVDGKNFKL AESIAILRYL AREFTVPDHW YPRDSRRRAR VDEYLEWQHS NTRLHCAGYV
RYVWRGPLRG ETMDPRVAKR LKAEMVGCLD FIETNVLQRD VHFIAGDEIS IADLVAACEI
EQPKLAGYDA RVGRPKLTAW MQRVKETTQP DYDEAHKVLN KFAPTAT
//
