ID Q5Q9W2_9CALI Unreviewed; 129 AA.
AC Q5Q9W2;
DT 04-JAN-2005, integrated into UniProtKB/TrEMBL.
DT 04-JAN-2005, sequence version 1.
DT 08-NOV-2023, entry version 64.
DE SubName: Full=RNA polymerase {ECO:0000313|EMBL:AAV84527.1};
DE Flags: Fragment;
OS Norovirus Hu/Nursing-home_A/28-12-2001/NL.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
OX NCBI_TaxID=298949 {ECO:0000313|EMBL:AAV84527.1};
RN [1] {ECO:0000313|EMBL:AAV84527.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=16126000; DOI=10.1016/j.jcv.2005.05.014;
RA Koek A.G., Bovee L.P.M.J., Hoek J.A.R., Bos A.J., Bruisten S.M.;
RT "Additional value of typing Noroviruses in gastroenteritis outbreaks in
RT Amsterdam, The Netherlands.";
RL J. Clin. Virol. 35:167-172(2006).
CC -!- FUNCTION: Viral genome-linked protein is covalently linked to the 5'-
CC end of the positive-strand, negative-strand genomic RNAs and subgenomic
CC RNA. Acts as a genome-linked replication primer. May recruit ribosome
CC to viral RNA thereby promoting viral proteins translation.
CC {ECO:0000256|ARBA:ARBA00025359}.
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DR EMBL; AY766261; AAV84527.1; -; Genomic_RNA.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR Pfam; PF00680; RdRP_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT DOMAIN 1..114
FT /note="RdRp catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50507"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAV84527.1"
FT NON_TER 129
FT /evidence="ECO:0000313|EMBL:AAV84527.1"
SQ SEQUENCE 129 AA; 14115 MW; 3896D276FF31A127 CRC64;
SRWDSTQQRA VLAAALEIMV KFSSEPHLAQ VVAEDLLSPS VVDVGDFKIS INEGLPSGVP
CTSQWNSIAH WLLTLCALSE VTNLSPDIIQ ANSLFSFYGD DEIVSTDVKL DPEKLTAKLK
EYGLKPTRP
//
