ID Q5SJL9_THET8 Unreviewed; 750 AA.
AC Q5SJL9;
DT 21-DEC-2004, integrated into UniProtKB/TrEMBL.
DT 21-DEC-2004, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=GGDEF domain protein {ECO:0000313|EMBL:BAD70812.1};
GN OrderedLocusNames=TTHA0989 {ECO:0000313|EMBL:BAD70812.1};
OS Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8).
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=300852 {ECO:0000313|EMBL:BAD70812.1, ECO:0000313|Proteomes:UP000000532};
RN [1] {ECO:0000313|EMBL:BAD70812.1, ECO:0000313|Proteomes:UP000000532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27634 / DSM 579 / HB8 {ECO:0000313|Proteomes:UP000000532};
RA Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T.,
RA Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.;
RT "Complete genome sequence of Thermus thermophilus HB8.";
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AP008226; BAD70812.1; -; Genomic_DNA.
DR RefSeq; YP_144255.1; NC_006461.1.
DR AlphaFoldDB; Q5SJL9; -.
DR EnsemblBacteria; BAD70812; BAD70812; BAD70812.
DR KEGG; ttj:TTHA0989; -.
DR PATRIC; fig|300852.9.peg.971; -.
DR eggNOG; COG1956; Bacteria.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG2203; Bacteria.
DR HOGENOM; CLU_370856_0_0_0; -.
DR Proteomes; UP000000532; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.450.40; -; 3.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF13185; GAF_2; 3.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00065; GAF; 3.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55781; GAF domain-like; 3.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000532};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 625..750
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 750 AA; 82444 MW; 81A1604086BBE180 CRC64;
MVAWGATMHW PLYVALAALA LGAALAGLRE SAAVPWFMVA VGLVASVFGL GAGLAALGLA
SLLLFFQGAM NPSSLAALLL AALLAHQVGE SLRRAHRRAK YLAQTHRLLA EALEALPKAQ
NREELLKSLP ERLARLGERG HVGVWVPEGQ GLRLLAARPP LSVETIPYGG VVGRAYREGR
PVYVPDVRRD PDYIAPPDHK ALAELALPLR ERGEVVAVLN LERDRPFPEE LQEGLKRFAQ
AVSLQLSRLA DEEERRLVAE LSLALQSASR LEEAAAKALA LLVRALGLEA GAFWEVRGAR
MVNLAAHGVE EPALRKVLEE GLPYGVGLAW RVYETRSPLF TARYAEEDRT VPALKALDWR
TFAALPVPTP GAPRARRIFV VGQRAERLWR RSEVDLLLLA CRTLGLGLER LTEKARHEAV
NRIFLELLEK PPEELYQAVL EEAIRQVPGA EAGSLLVWED GAYRYKAAFG YDLEGLKALA
FTREAQLKWY GLGEEKARQG EPRLLSVEER PIAEISHETA PPEVIDAAGK AEEIQANLCL
PIPYKGEVLA YLNLENLHDP KAFGEDSLEA ARFFATPLAT LLHEIRTRKL LEEAALTDPL
TGLPNRRAFD RFLEEELKRA ERYGYPLALA VMDLRGFKQV NDRLGHAVGD LALMKVAEAL
QREKRNGDRI FRWGGDEFAA LFPHTGKEGA LKAAFRYARA IEALCFGGLC LGVNIGLAAF
PEDGKTPDEL LSAADSRMYQ AKAQGLAVLA
//
