ID Q5U3M2_MOUSE Unreviewed; 313 AA.
AC Q5U3M2;
DT 07-DEC-2004, integrated into UniProtKB/TrEMBL.
DT 07-DEC-2004, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE SubName: Full=Hnrpa3 protein {ECO:0000313|EMBL:AAH85474.1};
GN Name=Hnrnpa3 {ECO:0000313|MGI:MGI:1917171};
GN Synonyms=Hnrpa3 {ECO:0000313|EMBL:AAH85474.1};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH85474.1};
RN [1] {ECO:0000313|EMBL:AAH85474.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6 {ECO:0000313|EMBL:AAH85474.1};
RC TISSUE=Eye {ECO:0000313|EMBL:AAH85474.1};
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; BC085474; AAH85474.1; -; mRNA.
DR RefSeq; NP_444493.1; NM_053263.1.
DR RefSeq; NP_666242.2; NM_146130.3.
DR AlphaFoldDB; Q5U3M2; -.
DR PeptideAtlas; Q5U3M2; -.
DR DNASU; 229279; -.
DR GeneID; 229279; -.
DR KEGG; mmu:229279; -.
DR AGR; MGI:1917171; -.
DR CTD; 220988; -.
DR MGI; MGI:1917171; Hnrnpa3.
DR OrthoDB; 3127428at2759; -.
DR BioGRID-ORCS; 229279; 12 hits in 78 CRISPR screens.
DR ChiTaRS; Hnrnpa3; mouse.
DR Genevisible; Q5U3M2; MM.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12582; RRM2_hnRNPA3; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR034516; hnRNPA1/3_RRM2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR48026:SF12; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A3; 1.
DR PANTHER; PTHR48026; HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 1.
PE 2: Evidence at transcript level;
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 60..139
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 138..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 269..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 313 AA; 32011 MW; D718296C353CF548 CRC64;
MRDPQTKRSR GFGFVTYSCV EEVDAAMCAR PHKVDGRVVE PKRAVSREDS VKPGAHLTVK
KIFVGGIKED TEEYNLRDYF EKYGKIETIE VMEDRQSGKK RGFAFVTFDD HDTVDKIVVQ
KYHTINGHNC EVKKALSKQE MQSAGSQRGR GGGSGNFMGR GGNFGGGGGN FGRGGNFGGR
GGYGGGGGGS RGSYGGGDGG YNGFGGDGGN YGGGPGYSSR GGYGGGGPGY GNQGGGYGGG
GGGYDGYNEG GNFGGGNYGG GGNYNDFGNY SGQQQSNYGP MKGGSFGGRS SGSPYGGGYG
SGGGSGGYGS RRF
//
