ID Q5UWF9_HALMA Unreviewed; 422 AA.
AC Q5UWF9;
DT 07-DEC-2004, integrated into UniProtKB/TrEMBL.
DT 07-DEC-2004, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Aminopeptidase {ECO:0000313|EMBL:AAV48394.1};
DE SubName: Full=M24 family peptidase {ECO:0000313|EMBL:QCP89915.1};
GN Name=pepB5 {ECO:0000313|EMBL:AAV48394.1};
GN OrderedLocusNames=rrnB0212 {ECO:0000313|EMBL:AAV48394.1};
GN ORFNames=E6P14_03350 {ECO:0000313|EMBL:QCP89915.1};
OS Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS B-1809) (Halobacterium marismortui).
OG Plasmid pHMA288 {ECO:0000313|EMBL:QCP89915.1}, and
OG Plasmid phma288 {ECO:0000313|Proteomes:UP000298722}.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Haloarcula.
OX NCBI_TaxID=272569 {ECO:0000313|EMBL:AAV48394.1, ECO:0000313|Proteomes:UP000001169};
RN [1] {ECO:0000313|EMBL:AAV48394.1, ECO:0000313|Proteomes:UP000001169}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43049 {ECO:0000313|EMBL:AAV48394.1}, and ATCC 43049 / DSM
RC 3752 / JCM 8966 / VKM B-1809 {ECO:0000313|Proteomes:UP000001169};
RX PubMed=15520287; DOI=10.1101/gr.2700304;
RA Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA Hood L., Ng W.V.;
RT "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT Dead Sea.";
RL Genome Res. 14:2221-2234(2004).
RN [2] {ECO:0000313|EMBL:QCP89915.1, ECO:0000313|Proteomes:UP000298722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43049 {ECO:0000313|EMBL:QCP89915.1,
RC ECO:0000313|Proteomes:UP000298722};
RC PLASMID=pHMA288 {ECO:0000313|EMBL:QCP89915.1}, and phma288
RC {ECO:0000313|Proteomes:UP000298722};
RA DasSarma S., DasSarma P., DasSarma S., Fomenkov A., Vincze T., Anton B.P.,
RA Roberts R.J.;
RT "Methylomes of two halophilic Archaea, Haloarcula marismortui and Haloferax
RT mediterranei.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AY596298; AAV48394.1; -; Genomic_DNA.
DR EMBL; CP039136; QCP89915.1; -; Genomic_DNA.
DR RefSeq; WP_011224945.1; NZ_CP039136.1.
DR AlphaFoldDB; Q5UWF9; -.
DR STRING; 272569.rrnB0212; -.
DR PaxDb; 272569-rrnB0212; -.
DR EnsemblBacteria; AAV48394; AAV48394; rrnB0212.
DR GeneID; 40151159; -.
DR KEGG; hma:rrnB0212; -.
DR PATRIC; fig|272569.17.peg.4221; -.
DR eggNOG; arCOG01000; Archaea.
DR HOGENOM; CLU_643438_0_0_2; -.
DR Proteomes; UP000001169; Chromosome II.
DR Proteomes; UP000298722; Plasmid phma288.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR CDD; cd01066; APP_MetAP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR46112:SF2; XAA-PRO AMINOPEPTIDASE P-RELATED; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000313|EMBL:AAV48394.1};
KW Hydrolase {ECO:0000313|EMBL:AAV48394.1};
KW Plasmid {ECO:0000313|EMBL:QCP89915.1};
KW Protease {ECO:0000313|EMBL:AAV48394.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001169}.
FT DOMAIN 31..132
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 190..403
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 422 AA; 48022 MW; E35AB2A3BFB3101E CRC64;
MYERDFMEGT RGTMAVDWEE RIDVKRMRRE RKERALDRLQ DSELGSILLI NDPNVRYVTG
LAMTGGSGAD HYTLLTEDGD VVHWDTADHA SNQRFNCPWL DDIRYACPGL GNVPRASGSA
SARDWLKDKM AETVYTAMEE YGVDREPMGI DVGNGTLIEK FENRGVDVDT SAATDIMLDA
RKTKTRDEIE CLRQVAAICE AGFQKITESA RPGKRESEVW GDAVSELWGH GAMAQGGYVT
SGPNTWPKHQ ANTTDRMIRP NDLVYADFYN IGYLGYRSCY YRTFSMGEPT QAQKDAYEKA
RDDLYDVLER IEPGATTDEI CKGFPDRDGE HMDWYDADEF WQMTTNHWAH GLGLQLYETP
LIWRGLSPDH PIEIEEGMTM AVETMQPAER QGVRVEEMVV VRENGVEILS EWPVSEITRI
DY
//
