ID Q5WZW3_LEGPL Unreviewed; 129 AA.
AC Q5WZW3;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=CidA/LrgA family protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=lpl0268 {ECO:0000313|EMBL:CAH14499.1};
OS Legionella pneumophila (strain Lens).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=297245 {ECO:0000313|EMBL:CAH14499.1, ECO:0000313|Proteomes:UP000002517};
RN [1] {ECO:0000313|EMBL:CAH14499.1, ECO:0000313|Proteomes:UP000002517}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lens {ECO:0000313|EMBL:CAH14499.1,
RC ECO:0000313|Proteomes:UP000002517};
RX PubMed=15467720; DOI=10.1038/ng1447;
RA Cazalet C., Rusniok C., Bruggemann H., Zidane N., Magnier A., Ma L.,
RA Tichit M., Jarraud S., Bouchier C., Vandenesch F., Kunst F., Etienne J.,
RA Glaser P., Buchrieser C.;
RT "Evidence in the Legionella pneumophila genome for exploitation of host
RT cell functions and high genome plasticity.";
RL Nat. Genet. 36:1165-1173(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CR628337; CAH14499.1; -; Genomic_DNA.
DR RefSeq; WP_011214533.1; NC_006369.1.
DR AlphaFoldDB; Q5WZW3; -.
DR KEGG; lpf:lpl0268; -.
DR LegioList; lpl0268; -.
DR HOGENOM; CLU_113736_3_1_6; -.
DR Proteomes; UP000002517; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR005538; LrgA/CidA.
DR PANTHER; PTHR33931:SF2; HOLIN-LIKE PROTEIN CIDA; 1.
DR PANTHER; PTHR33931; HOLIN-LIKE PROTEIN CIDA-RELATED; 1.
DR Pfam; PF03788; LrgA; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 129 AA; 14504 MW; DD18E6A52F6E15F3 CRC64;
MANKIQQNSF FQIILVGLFW LASELLLKLV KLPLSGGILG LGIVLLLLAT NCLKLNRIRR
GAELLLANML LFFIPGVLAI LEHQEFIGLL GLKILFIILL STITVMLVTA LVVDYCYRWR
THHAKQHSL
//
