ID Q5XBI2_STRP6 Unreviewed; 83 AA.
AC Q5XBI2;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE RecName: Full=Glutaredoxin-like protein NrdH {ECO:0000256|ARBA:ARBA00017945};
GN OrderedLocusNames=M6_Spy1096 {ECO:0000313|EMBL:AAT87231.1};
OS Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=286636 {ECO:0000313|EMBL:AAT87231.1, ECO:0000313|Proteomes:UP000001167};
RN [1] {ECO:0000313|EMBL:AAT87231.1, ECO:0000313|Proteomes:UP000001167}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-946 / MGAS10394 {ECO:0000313|Proteomes:UP000001167};
RX PubMed=15272401; DOI=10.1086/422697;
RA Banks D.J., Porcella S.F., Barbian K.D., Beres S.B., Philips L.E.,
RA Voyich J.M., DeLeo F.R., Martin J.M., Somerville G.A., Musser J.M.;
RT "Progress toward characterization of the group A Streptococcus metagenome:
RT complete genome sequence of a macrolide-resistant serotype M6 strain.";
RL J. Infect. Dis. 190:727-738(2004).
CC -!- FUNCTION: Electron transport system for the ribonucleotide reductase
CC system NrdEF. {ECO:0000256|ARBA:ARBA00002292}.
CC -!- SIMILARITY: Belongs to the ArsC family. {ECO:0000256|PROSITE-
CC ProRule:PRU01282}.
CC -!- SIMILARITY: Belongs to the glutaredoxin family.
CC {ECO:0000256|ARBA:ARBA00007787}.
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DR EMBL; CP000003; AAT87231.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5XBI2; -.
DR KEGG; spa:M6_Spy1096; -.
DR HOGENOM; CLU_026126_9_0_9; -.
DR Proteomes; UP000001167; Chromosome.
DR GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR CDD; cd02976; NrdH; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR006660; Arsenate_reductase-like.
DR InterPro; IPR011909; GlrX_NrdH.
DR InterPro; IPR002109; Glutaredoxin.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR NCBIfam; TIGR02194; GlrX_NrdH; 1.
DR PANTHER; PTHR34386; GLUTAREDOXIN; 1.
DR PANTHER; PTHR34386:SF1; GLUTAREDOXIN-LIKE PROTEIN NRDH; 1.
DR Pfam; PF00462; Glutaredoxin; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51353; ARSC; 1.
DR PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 13..68
FT /note="Glutaredoxin"
FT /evidence="ECO:0000259|Pfam:PF00462"
SQ SEQUENCE 83 AA; 9448 MW; 75E1BDFD5C0F9A01 CRC64;
MEPLLILEGQ DMITVYSKNN CMQCKMTKKF LEQHGANFQE INIDEHPEKV DYVKSLGFTS
APVIEADNLV FSGFQPAKLK ELI
//
