GenomeNet

Database: UniProt
Entry: Q5Y5Q1_9EURO
LinkDB: Q5Y5Q1_9EURO
Original site: Q5Y5Q1_9EURO 
ID   Q5Y5Q1_9EURO            Unreviewed;        88 AA.
AC   Q5Y5Q1;
DT   23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT   23-NOV-2004, sequence version 1.
DT   24-JAN-2024, entry version 71.
DE   SubName: Full=Beta tubulin {ECO:0000313|EMBL:AAU95109.1};
DE   Flags: Fragment;
OS   Penicillium tricolor.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=60170 {ECO:0000313|EMBL:AAU95109.1};
RN   [1] {ECO:0000313|EMBL:AAU95109.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CBS 63695 {ECO:0000313|EMBL:AAU95109.1};
RA   Samson R.A., Seifert K.A., Kuijpers A.F.A., Houbraken J.A.M.P.,
RA   Frisvad J.C.;
RT   "Phylogenetic analysis of Penicillium subgenus Penicillium using partial b-
RT   tubulin sequences.";
RL   Stud. Mycol. 49:175-200(2004).
CC   -!- FUNCTION: Tubulin is the major constituent of microtubules, a cylinder
CC       consisting of laterally associated linear protofilaments composed of
CC       alpha- and beta-tubulin heterodimers. Microtubules grow by the addition
CC       of GTP-tubulin dimers to the microtubule end, where a stabilizing cap
CC       forms. Below the cap, tubulin dimers are in GDP-bound state, owing to
CC       GTPase activity of alpha-tubulin. {ECO:0000256|ARBA:ARBA00034296}.
CC   -!- SUBUNIT: Dimer of alpha and beta chains. A typical microtubule is a
CC       hollow water-filled tube with an outer diameter of 25 nm and an inner
CC       diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to
CC       form protofilaments running lengthwise along the microtubule wall with
CC       the beta-tubulin subunit facing the microtubule plus end conferring a
CC       structural polarity. Microtubules usually have 13 protofilaments but
CC       different protofilament numbers can be found in some organisms and
CC       specialized cells. {ECO:0000256|ARBA:ARBA00011747}.
CC   -!- SIMILARITY: Belongs to the tubulin family.
CC       {ECO:0000256|ARBA:ARBA00009636}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY674311; AAU95109.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q5Y5Q1; -.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   Gene3D; 3.40.50.1440; Tubulin/FtsZ, GTPase domain; 1.
DR   InterPro; IPR002453; Beta_tubulin.
DR   InterPro; IPR000217; Tubulin.
DR   InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR   InterPro; IPR003008; Tubulin_FtsZ_GTPase.
DR   PANTHER; PTHR11588; TUBULIN; 1.
DR   PANTHER; PTHR11588:SF429; TUBULIN BETA-1 CHAIN-RELATED; 1.
DR   Pfam; PF00091; Tubulin; 1.
DR   PRINTS; PR01163; BETATUBULIN.
DR   PRINTS; PR01161; TUBULIN.
DR   SUPFAM; SSF52490; Tubulin nucleotide-binding domain-like; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          1..87
FT                   /note="Tubulin/FtsZ GTPase"
FT                   /evidence="ECO:0000259|Pfam:PF00091"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAU95109.1"
FT   NON_TER         88
FT                   /evidence="ECO:0000313|EMBL:AAU95109.1"
SQ   SEQUENCE   88 AA;  9622 MW;  A959D9FAB7A4521F CRC64;
     WQTISGEHGL DGDGQYNGTS DLQLERMNVY FNHASGDKYV PRAVLVDLEP GTMDAVRSGP
     FGKLFRPDNF VFGQSGAGNN WAKGHYTG
//
DBGET integrated database retrieval system