ID Q5YRE2_NOCFA Unreviewed; 369 AA.
AC Q5YRE2;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE SubName: Full=Putative geranylgeranyl pyrophosphate synthase {ECO:0000313|EMBL:BAD59249.1};
GN Name=crtE2 {ECO:0000313|EMBL:BAD59249.1};
GN OrderedLocusNames=NFA_44000 {ECO:0000313|EMBL:BAD59249.1};
OS Nocardia farcinica (strain IFM 10152).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=247156 {ECO:0000313|EMBL:BAD59249.1, ECO:0000313|Proteomes:UP000006820};
RN [1] {ECO:0000313|EMBL:BAD59249.1, ECO:0000313|Proteomes:UP000006820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 10152 {ECO:0000313|EMBL:BAD59249.1,
RC ECO:0000313|Proteomes:UP000006820};
RX PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA Shiba T., Hattori M.;
RT "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC -!- PATHWAY: Isoprenoid biosynthesis. {ECO:0000256|ARBA:ARBA00005128}.
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP006618; BAD59249.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5YRE2; -.
DR STRING; 247156.NFA_44000; -.
DR KEGG; nfa:NFA_44000; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_2_1_11; -.
DR Proteomes; UP000006820; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001:SF88; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000006820};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 369 AA; 39487 MW; CAC51E3A177228F1 CRC64;
MAGETMIDRP VHTEAPPVPE HPAAWCTRMR DDTARVLDDF VRARRREHLG APETAVLGQV
IGDFVAGGKY LRSALHLAGW STVAPVGAAA IRAAASAELL HCFALMQDDV MDESARRRGR
PAAHVRFAQW HARQGFSGSS DRFGESAATL AADLCLVWAE QLLRESGVDA AALARALPRY
DAMRSELAVG QFRDLVNDAR RRPALADVLA VARAKSGHYT VRRPLELGAE LAGAPPAVLA
ALGRYGVAIG EAFQVRDDLL GVFGDPGATG KPVGADLRNG KATTVVVLAR EYADGVTRRE
LARLAALPEL GAEEIARYVR VIAETGAPRR LELLIAHRLR EGLAAIAGLE PGARAVLTHL
AHACTDRSR
//
