ID Q5YW13_NOCFA Unreviewed; 633 AA.
AC Q5YW13;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=Putative monooxygenase {ECO:0000313|EMBL:BAD57628.1};
GN OrderedLocusNames=NFA_27810 {ECO:0000313|EMBL:BAD57628.1};
OS Nocardia farcinica (strain IFM 10152).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=247156 {ECO:0000313|EMBL:BAD57628.1, ECO:0000313|Proteomes:UP000006820};
RN [1] {ECO:0000313|EMBL:BAD57628.1, ECO:0000313|Proteomes:UP000006820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 10152 {ECO:0000313|EMBL:BAD57628.1,
RC ECO:0000313|Proteomes:UP000006820};
RX PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA Shiba T., Hattori M.;
RT "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the PheA/TfdB FAD monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00007801}.
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DR EMBL; AP006618; BAD57628.1; -; Genomic_DNA.
DR RefSeq; WP_011209313.1; NC_006361.1.
DR AlphaFoldDB; Q5YW13; -.
DR STRING; 247156.NFA_27810; -.
DR GeneID; 61133516; -.
DR KEGG; nfa:NFA_27810; -.
DR eggNOG; COG0654; Bacteria.
DR HOGENOM; CLU_009665_9_2_11; -.
DR OrthoDB; 8670884at2; -.
DR Proteomes; UP000006820; Chromosome.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR CDD; cd02979; PHOX_C; 1.
DR Gene3D; 3.40.30.20; -; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012941; Phe_hydrox_C_dim_dom.
DR InterPro; IPR038220; PHOX_C_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43004:SF6; FAD_NAD(P)-BINDING OXIDOREDUCTASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR43004; TRK SYSTEM POTASSIUM UPTAKE PROTEIN; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR Pfam; PF07976; Phe_hydrox_dim; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Monooxygenase {ECO:0000313|EMBL:BAD57628.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006820}.
FT DOMAIN 32..404
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
FT DOMAIN 435..594
FT /note="Phenol hydroxylase C-terminal dimerisation"
FT /evidence="ECO:0000259|Pfam:PF07976"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 633 AA; 69813 MW; D9A3008FAA16D8EB CRC64;
MQFHHHGYVS GDPRVQPAAG VGIDRPADLP DEVDVLIVGA GPAGMIAAAQ LAQFPTINAR
IIDRRPGRLE VGQADGIQAR SVETFQAFGF AERITAEAYR ITEMAFWKPD PQNPSNIVRT
ARTPDDETGI SEFPHLIVNQ ARVLDYFAEA ARNAPARLEP DYGYEFVTLE VAEEGERPVT
VTLRHSAGER AGQERIVKAK YVIGCDGARS RVREAIGRRF IGNQANHAWG VMDVLAETDF
PDIRLKCAIQ SHDGGSILHI PREGNFLFRM YVDLGEVPEG DNGRIRQTSQ EEVEARANKI
LHPYTLTVKH VAWRSVYEVG HRVTDKFDDV PPEQCGTRSP RVFITGDACH THSAKAGQGM
NVSMQDGWNI AWKVAHVLDG RAPETILDTY SAERQVIAQN LIDFDREWST LMATRPEEMA
DPSQLEEFYV KTAEFPAGFM TQYAPSMLVA EARHQALATG FPVGKRFKSN LVTRVCDANP
KHLGHHARAD GRWRIYVFAD APAAGAPSKT TELAEWLATA PSSPLVAYTP EGADLDAWFD
VKVIYQQDHT GVDLGAVPAV FLPKVGPFQV TDYEKVYAAD PADDIFTARG ISRDGAIVVV
RPDQYVADVL PLDATDELAA FFDGVFVKRL STV
//
