ID Q5Z390_NOCFA Unreviewed; 763 AA.
AC Q5Z390;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Putative membrane protein {ECO:0000313|EMBL:BAD55101.1};
GN OrderedLocusNames=NFA_2590 {ECO:0000313|EMBL:BAD55101.1};
OS Nocardia farcinica (strain IFM 10152).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=247156 {ECO:0000313|EMBL:BAD55101.1, ECO:0000313|Proteomes:UP000006820};
RN [1] {ECO:0000313|EMBL:BAD55101.1, ECO:0000313|Proteomes:UP000006820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 10152 {ECO:0000313|EMBL:BAD55101.1,
RC ECO:0000313|Proteomes:UP000006820};
RX PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA Shiba T., Hattori M.;
RT "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AP006618; BAD55101.1; -; Genomic_DNA.
DR RefSeq; WP_011206788.1; NC_006361.1.
DR AlphaFoldDB; Q5Z390; -.
DR STRING; 247156.NFA_2590; -.
DR GeneID; 61131102; -.
DR KEGG; nfa:NFA_2590; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_1_1_11; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000006820; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006820};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 211..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 583..604
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 624..645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 666..686
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 698..722
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 227..360
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 763 AA; 80569 MW; 16D878B8773E8796 CRC64;
MSVFLYRWGK FAFRRKWIVL PVWLALFLIL GGLGAQLREP MTDDFSLPNL PSERATEILD
KHFPGMSEAF AFDAVTGTYV IGAPEGQRLT DPANREAITA MIGRLEQLDI VDHAEPIVDP
ITATEQMGCL IPDPDPAECG SAPLNVLNQT APATVAYFSV PFTIAEFADI TAQDRAAAYG
VADAARQAGL TVEMSGSIAI EEGGPSGKAE MIGMAVAFVV MIVAFGAIVA AFVPIVTAVV
GLGAATSLIF LGTSVVSIPT FTTFLASMIG IALSIDYALF IVSRYKHELA VQDSPEEAAG
TALGTAGSAV VFAGLTVIIA LAGLSIVGVR FLTFMGLGGA VAAAFAVLVA LTLMPALLGA
LGRFLFTPKL PLVAQHDPED DTVVTNGMRV AKLIGRAPAL TLLLSVVVLG LLAAPAVNLD
LGLPGEDSMA KTTTVRKAYE LRTAGFGEGS NGVLQVAVDL SGVPEDRRAE ALTALRDKLA
SYPDMDYVSR PTPSADGQGA LINGVPTAGP NDQRTKDLVR DARADEAALN EEFGMEYGVT
GTTAIYADID HVLLGKIVPY MAIVAGAAFV LLILVFRSIL VPLTGALGFL LSMAATFGAT
VLIFQEGRFG LIDDPHPIVS FLPIMLIGLV FGLAMDYQVF LVTRIREEYV HGAEPRTAMI
NGYHHGARVV TAAAVIMISV FGSFLLETDA TAKSMGFALA AGVLLDAFFV RMLLIPSLLA
LLGDKAWWMP RWLDRIVPDI DVEGAKLYAL RAPAADKERA PVS
//
