ID Q5ZSJ5_LEGPH Unreviewed; 384 AA.
AC Q5ZSJ5;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Metal-activated pyridoxal enzyme {ECO:0000313|EMBL:AAU28582.1};
GN OrderedLocusNames=lpg2522 {ECO:0000313|EMBL:AAU28582.1};
OS Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC
OS 33152 / DSM 7513).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=272624 {ECO:0000313|EMBL:AAU28582.1, ECO:0000313|Proteomes:UP000000609};
RN [1] {ECO:0000313|EMBL:AAU28582.1, ECO:0000313|Proteomes:UP000000609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Philadelphia 1 / ATCC 33152 / DSM 7513
RC {ECO:0000313|Proteomes:UP000000609};
RX PubMed=15448271; DOI=10.1126/science.1099776;
RA Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G.,
RA Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V.,
RA Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A.,
RA Chou I.C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A.,
RA Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A.,
RA Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A.,
RA Russo J.J.;
RT "The genomic sequence of the accidental pathogen Legionella pneumophila.";
RL Science 305:1966-1968(2004).
CC -!- SIMILARITY: Belongs to the DSD1 family.
CC {ECO:0000256|ARBA:ARBA00005323}.
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DR EMBL; AE017354; AAU28582.1; -; Genomic_DNA.
DR RefSeq; YP_096529.1; NC_002942.5.
DR AlphaFoldDB; Q5ZSJ5; -.
DR STRING; 272624.lpg2522; -.
DR PaxDb; 272624-lpg2522; -.
DR KEGG; lpn:lpg2522; -.
DR PATRIC; fig|272624.6.peg.2680; -.
DR eggNOG; COG3616; Bacteria.
DR HOGENOM; CLU_031639_2_1_6; -.
DR OrthoDB; 9772497at2; -.
DR Proteomes; UP000000609; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProt.
DR CDD; cd06819; PLPDE_III_LS_D-TA; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR Gene3D; 2.40.37.20; D-serine dehydratase-like domain; 1.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR026956; D-ser_dehydrat-like_dom.
DR InterPro; IPR042208; D-ser_dehydrat-like_sf.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR28004:SF2; D-SERINE DEHYDRATASE; 1.
DR PANTHER; PTHR28004; ZGC:162816-RELATED; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR Pfam; PF14031; D-ser_dehydrat; 1.
DR SMART; SM01119; D-ser_dehydrat; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000609}.
FT DOMAIN 275..367
FT /note="D-serine dehydratase-like"
FT /evidence="ECO:0000259|SMART:SM01119"
SQ SEQUENCE 384 AA; 43077 MW; 61CB25B2D34225D7 CRC64;
MNFVMNYLMK EKYIGLHKIE LNTPCLVIDY EKLKYNLKVM QQHGFEWGIG IRPHCKTHKC
TQIARLQLEY GAIGISAAKL SEAEVLVSKQ ITNVLITSPI VSEAKYSRLF NCLKSAPDLM
LVVDGKDNIR MLNELGKSLN QPVYVLLDID SGIGRTGINP EVALEYGHFI NSMNWLKLKG
IQCYAGHLQH IQNYEERKAF SLRIMDMASR IVKSFRDANL PCEILTGTGT GTFDIDVEAS
EVTEIQPGSY AVMDVEYGSI GSKNNPSSFQ PFKNSMTLLT SVISSNRKEH ATVDAGTKSI
YVDPHHKPHI ISHPGLVYDW GGFGDEHGKV FSCEGGSHFL QNGDVLELIV PHCDPTINLY
DKFYITENNV VVDIWDIDMR GKSQ
//
