ID Q5ZTL7_LEGPH Unreviewed; 172 AA.
AC Q5ZTL7;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=F-box protein {ECO:0000313|EMBL:AAU28210.1};
GN Name=legAU13 {ECO:0000313|EMBL:AAU28210.1};
GN OrderedLocusNames=lpg2144 {ECO:0000313|EMBL:AAU28210.1};
OS Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC
OS 33152 / DSM 7513).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=272624 {ECO:0000313|EMBL:AAU28210.1, ECO:0000313|Proteomes:UP000000609};
RN [1] {ECO:0000313|EMBL:AAU28210.1, ECO:0000313|Proteomes:UP000000609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Philadelphia 1 / ATCC 33152 / DSM 7513
RC {ECO:0000313|Proteomes:UP000000609};
RX PubMed=15448271; DOI=10.1126/science.1099776;
RA Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G.,
RA Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V.,
RA Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A.,
RA Chou I.C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A.,
RA Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A.,
RA Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A.,
RA Russo J.J.;
RT "The genomic sequence of the accidental pathogen Legionella pneumophila.";
RL Science 305:1966-1968(2004).
RN [2] {ECO:0007829|PDB:5K34, ECO:0007829|PDB:5K35}
RP X-RAY CRYSTALLOGRAPHY (1.15 ANGSTROMS) OF 54-168.
RX PubMed=28111017; DOI=10.1016/j.str.2016.12.015;
RA Wong K., Perpich J.D., Kozlov G., Cygler M., Abu Kwaik Y., Gehring K.;
RT "Structural Mimicry by a Bacterial F Box Effector Hijacks the Host
RT Ubiquitin-Proteasome System.";
RL Structure 25:376-383(2017).
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DR EMBL; AE017354; AAU28210.1; -; Genomic_DNA.
DR RefSeq; WP_010947855.1; NC_002942.5.
DR RefSeq; YP_096157.1; NC_002942.5.
DR PDB; 5K34; X-ray; 1.15 A; A=54-168.
DR PDB; 5K35; X-ray; 2.85 A; A=1-168.
DR PDBsum; 5K34; -.
DR PDBsum; 5K35; -.
DR AlphaFoldDB; Q5ZTL7; -.
DR SMR; Q5ZTL7; -.
DR PaxDb; 272624-lpg2144; -.
DR GeneID; 66491274; -.
DR KEGG; lpn:lpg2144; -.
DR PATRIC; fig|272624.6.peg.2250; -.
DR eggNOG; COG0666; Bacteria.
DR HOGENOM; CLU_1693312_0_0_6; -.
DR OrthoDB; 5644680at2; -.
DR Proteomes; UP000000609; Chromosome.
DR CDD; cd09917; F-box_SF; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF12937; F-box-like; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:5K34, ECO:0007829|PDB:5K35};
KW Reference proteome {ECO:0000313|Proteomes:UP000000609}.
FT DOMAIN 3..50
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
SQ SEQUENCE 172 AA; 19995 MW; 5BC70FF9B321AD7C CRC64;
MKKNFFSDLP EETIVNTLSF LKANTLARIA QTCQFFNRLA NDKHLELHQL RQQHIKRELW
GNLMVAARSN NLEEVKKILK KGIDPTQTNS YHLNRTPLLA AIEGKAYQTA NYLWRKYTFD
PNFKDNYGDS PISLLKKQLA NPAFKDKEKK QIRALIRGMQ EEKIAQSKCL VC
//
