ID Q603Q2_METCA Unreviewed; 543 AA.
AC Q603Q2;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=HAMP domain protein {ECO:0000313|EMBL:AAU91163.1};
GN OrderedLocusNames=MCA2750 {ECO:0000313|EMBL:AAU91163.1};
OS Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylococcus.
OX NCBI_TaxID=243233 {ECO:0000313|EMBL:AAU91163.1, ECO:0000313|Proteomes:UP000006821};
RN [1] {ECO:0000313|EMBL:AAU91163.1, ECO:0000313|Proteomes:UP000006821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33009 / NCIMB 11132 / Bath
RC {ECO:0000313|Proteomes:UP000006821};
RX PubMed=15383840; DOI=10.1371/journal.pbio.0020303;
RA Ward N.L., Larsen O., Sakwa J., Bruseth L., Khouri H.M., Durkin A.S.,
RA Dimitrov G., Jiang L., Scanlan D., Kang K.H., Lewis M.R., Nelson K.E.,
RA Methe B.A., Wu M., Heidelberg J.F., Paulsen I.T., Fouts D.E., Ravel J.,
RA Tettelin H., Ren Q., Read T.D., DeBoy R.T., Seshadri R., Salzberg S.L.,
RA Jensen H.B., Birkeland N.K., Nelson W.C., Dodson R.J., Grindhaug S.H.,
RA Holt I.E., Eidhammer I., Jonasen I., Vanaken S., Utterback T.R.,
RA Feldblyum T.V., Fraser C.M., Lillehaug J.R., Eisen J.A.;
RT "Genomic insights into methanotrophy: the complete genome sequence of
RT Methylococcus capsulatus (Bath).";
RL PLoS Biol. 2:1616-1628(2004).
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DR EMBL; AE017282; AAU91163.1; -; Genomic_DNA.
DR AlphaFoldDB; Q603Q2; -.
DR STRING; 243233.MCA2750; -.
DR KEGG; mca:MCA2750; -.
DR eggNOG; COG2208; Bacteria.
DR eggNOG; COG3850; Bacteria.
DR HOGENOM; CLU_026432_1_0_6; -.
DR Proteomes; UP000006821; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF07228; SpoIIE; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006821};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 170..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 194..258
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 320..535
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
SQ SEQUENCE 543 AA; 59678 MW; E0BAD226284513B8 CRC64;
MLGLLVSGVF TLTVVGLILQ KQSLESELAK RVELMRANLL ERGTAFSKLV ENEVENDVAA
FNFSHIQEVL SHSPQLDYAI LTNTEGVAFV HTRSPDLQQE KLQGEADRYA LRQTGLTHRE
YPDQNAIEFI LPIHFGAKPW GVLRLGFSLE TLRQEIANSR AEIEAATRRV VLLGTGIAGI
FIVIGSGIVV LVSNALSRPL IRLTRSVRAL ARGNYDDAAH LLETELPQRM GHAAPTDEIG
ILAGSFVQMA GEIRRSHEQL EEYNRTLEDK VRVRTEELVE AYRKQKELEN EILQESLRLA
RDIQMGMMST AFPRFAKGSP VDLYAMVDPA REVGGDFYDF LYLDGRTLLI AIGDVSGKGM
AAALFMVKVK TMIRAVTSAH GSPREILQAV NPELCRENDV GMFVTVFLAT LDVETGRLVY
SYGGHNRPVL LGRDGSVEML TGDTAVALGV FDDIEFSEQE RVLQPGAALV MYTDGVNEAM
NGESELFGDS RLLAALRGRT REDASELVDA VISRVRAHAG TAEQSDDITL IAVRRAPSAG
VTV
//
