ID Q63GJ3_BACCZ Unreviewed; 674 AA.
AC Q63GJ3;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 122.
DE SubName: Full=Chitinase {ECO:0000313|EMBL:AAU19880.1};
DE EC=3.2.1.14 {ECO:0000313|EMBL:AAU19880.1};
GN Name=chiA {ECO:0000313|EMBL:AAU19880.1};
GN OrderedLocusNames=BCE33L0359 {ECO:0000313|EMBL:AAU19880.1};
OS Bacillus cereus (strain ZK / E33L).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=288681 {ECO:0000313|EMBL:AAU19880.1, ECO:0000313|Proteomes:UP000002612};
RN [1] {ECO:0000313|Proteomes:UP000002612}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZK / E33L {ECO:0000313|Proteomes:UP000002612};
RX PubMed=16621833; DOI=10.1128/JB.188.9.3382-3390.2006;
RA Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Brown N.,
RA Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C.,
RA Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A.,
RA Green L.D., Hill K.K., Hitchcock P., Jackson P.J., Keim P.,
RA Kewalramani A.R., Longmire J., Lucas S., Malfatti S., McMurry K.,
RA Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T.,
RA Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Rubin E.,
RA Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA Ticknor L.O., Wills P.L., Brettin T.S., Gilna P.;
RT "Pathogenomic sequence analysis of Bacillus cereus and Bacillus
RT thuringiensis isolates closely related to Bacillus anthracis.";
RL J. Bacteriol. 188:3382-3390(2006).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC class II subfamily. {ECO:0000256|ARBA:ARBA00009121}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000001; AAU19880.1; -; Genomic_DNA.
DR RefSeq; WP_000837176.1; NZ_CP009968.1.
DR AlphaFoldDB; Q63GJ3; -.
DR CAZy; CBM2; Carbohydrate-Binding Module Family 2.
DR CAZy; GH18; Glycoside Hydrolase Family 18.
DR KEGG; bcz:BCE33L0359; -.
DR PATRIC; fig|288681.22.peg.5244; -.
DR Proteomes; UP000002612; Chromosome.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0030247; F:polysaccharide binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd00063; FN3; 1.
DR CDD; cd06548; GH18_chitinase; 1.
DR Gene3D; 2.60.40.290; -; 1.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR001919; CBD2.
DR InterPro; IPR008965; CBM2/CBM3_carb-bd_dom_sf.
DR InterPro; IPR012291; CBM2_carb-bd_dom_sf.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR11177; CHITINASE; 1.
DR PANTHER; PTHR11177:SF317; CHITINASE 11; 1.
DR Pfam; PF00553; CBM_2; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00637; CBD_II; 1.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49384; Carbohydrate-binding domain; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS51173; CBM2; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489}.
FT DOMAIN 39..476
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT DOMAIN 484..576
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 572..674
FT /note="CBM2"
FT /evidence="ECO:0000259|PROSITE:PS51173"
SQ SEQUENCE 674 AA; 74136 MW; F92DD7914C9D6427 CRC64;
MKSKKFTLLL LSLLLFLPLF LTNFITPNVL LADSQKQGQK IVGYFPSWGI YGRNYQVADI
DASKLTHLNY AFADICWNGK HGNPSTHPDN PNKQTWNCKE SGVPLQNKEV PNGTLVLGEP
WADVTKSYPG SGTTWEDCDK YARCGNFGEL KRLKAKYPHL KTIISVGGWT WSNRFSDMAA
DEKTRKVFAD STVDFLREYG FDGVDLDWEY PGVETIPGGS YRPEDKQNFT LLLQDVRNAL
TKAGAEDGKQ YLLTIASGAS QRYADHTELK KISQILDWIN IMTYDFHGGW EATSNHNAAL
YKDPNDPAAD TKFYVDGAID IYTNEGVPAD KLVLGVPFYG RGWKSCGKEN NGQYQPCKPG
SDGKLASKGT WDDYSTGDTG VYDYGDLAAN YVNKNGFVRG WNDVAKVPYL YNATTGTFIS
YDDNESMKYK TDYIKTKGLS GAMFWELSGD CRTSPKYSCS GPKLLDTLVK ELLGGPITQK
DIEPPTNVKN IAVTNKNSNS VQLNWTASTD NVGVTEYEIT AGEEKWSTTT NSIAIKNLKP
NTEYTFSILA KDAAGNKSQP TSILVKTDDA NTTPPGGNSN ATFSVTSNWG SGYNFSIVIK
NSGTTSIKNW KLEFDYNGNL TQVWDSKISS KINNHYVITN VGWNGEIPPG GSITIGGAGT
GTPAELVNAS ISEN
//
