ID Q63J26_BURPS Unreviewed; 295 AA.
AC Q63J26;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 113.
DE SubName: Full=Cat operon LysR-family transcriptional activator {ECO:0000313|EMBL:CAH39368.1};
GN OrderedLocusNames=BPSS1890 {ECO:0000313|EMBL:CAH39368.1};
OS Burkholderia pseudomallei (strain K96243).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=272560 {ECO:0000313|EMBL:CAH39368.1, ECO:0000313|Proteomes:UP000000605};
RN [1] {ECO:0000313|EMBL:CAH39368.1, ECO:0000313|Proteomes:UP000000605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K96243 {ECO:0000313|EMBL:CAH39368.1,
RC ECO:0000313|Proteomes:UP000000605};
RX PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.M., Atkins T.,
RA Crossman L.C., Pitt T., Churcher C., Mungall K., Bentley S.D., Sebaihia M.,
RA Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F.,
RA Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crosset B.,
RA Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H.,
RA Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C.,
RA Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S.,
RA Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT pseudomallei.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; BX571966; CAH39368.1; -; Genomic_DNA.
DR RefSeq; WP_004529133.1; NZ_CP009537.1.
DR RefSeq; YP_111896.1; NC_006351.1.
DR AlphaFoldDB; Q63J26; -.
DR STRING; 272560.BPSS1890; -.
DR GeneID; 56529692; -.
DR KEGG; bps:BPSS1890; -.
DR PATRIC; fig|272560.51.peg.5356; -.
DR eggNOG; COG0583; Bacteria.
DR Proteomes; UP000000605; Chromosome 2.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08445; PBP2_BenM_CatM_CatR; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF0; HCA OPERON TRANSCRIPTIONAL ACTIVATOR HCAR; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000605}.
FT DOMAIN 1..58
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 295 AA; 32293 MW; 68282633A229C68B CRC64;
MELRQLRYFI AVAEEMNITR AAQRLHMTQP PLSRQLQLIE DEIGLPLFER GARPLKLTDA
GRVLYAQARR VLEQADELAP LTRRLAQAAE RIVIGFVPST LYGALPEVIR AFREAAPAVE
LSLIEMFTLE QLGALKGGRI DIGFGRLRFD DDRLVREVLV EERLIAALPD GHPLAAPDAS
ISLADIAGQT LIVYPSTPRP SFADQQLSAL RDGGLAPAAV HEVRELQTAL GLVAAQVGVS
LVPESVEGVR VKGVAYRRLP EPVATSPIIL SRRLHDESRA TALFCSLARE LMAGH
//
