ID Q63N65_BURPS Unreviewed; 299 AA.
AC Q63N65;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE SubName: Full=LysR-family transcriptional regulator {ECO:0000313|EMBL:CAH37887.1};
GN OrderedLocusNames=BPSS0431 {ECO:0000313|EMBL:CAH37887.1};
OS Burkholderia pseudomallei (strain K96243).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=272560 {ECO:0000313|EMBL:CAH37887.1, ECO:0000313|Proteomes:UP000000605};
RN [1] {ECO:0000313|EMBL:CAH37887.1, ECO:0000313|Proteomes:UP000000605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K96243 {ECO:0000313|EMBL:CAH37887.1,
RC ECO:0000313|Proteomes:UP000000605};
RX PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.M., Atkins T.,
RA Crossman L.C., Pitt T., Churcher C., Mungall K., Bentley S.D., Sebaihia M.,
RA Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F.,
RA Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crosset B.,
RA Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H.,
RA Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C.,
RA Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S.,
RA Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT pseudomallei.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; BX571966; CAH37887.1; -; Genomic_DNA.
DR RefSeq; WP_004525453.1; NZ_CP009537.1.
DR RefSeq; YP_110454.1; NC_006351.1.
DR AlphaFoldDB; Q63N65; -.
DR STRING; 272560.BPSS0431; -.
DR GeneID; 56531120; -.
DR KEGG; bps:BPSS0431; -.
DR PATRIC; fig|272560.51.peg.6570; -.
DR eggNOG; COG0583; Bacteria.
DR Proteomes; UP000000605; Chromosome 2.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08422; PBP2_CrgA_like; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30537:SF5; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TTDR-RELATED; 1.
DR PANTHER; PTHR30537; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000605}.
FT DOMAIN 1..58
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 299 AA; 32816 MW; 9CB5533B351DFCE5 CRC64;
MQFDDLRIFV ATVEAGSFTG AADKLLLSKQ FVSRRVMALE ASLGVRLLVR NTRKLAVTEL
GHELHARATR ILADIAETEE AMSARRGDLR GTLKISAPMS FGIAHLSPLI AEFLVRHPAV
RLHVELSDRH VDLIGEGFDL ALRIGALPDS TLIARRLGEL RMVACCSPAY RRKHGAPATP
ADLHGRACLL YGQEGRTGWE FMIDGARRTF EVQGALLANN GDVVRDAAVA GLGIALLPHF
IVAHALDAGR LVAVLEPFAQ APLPINAVYP QHRQDMAACR TFLGFIEERL RERFAKPRR
//
