ID Q63YS1_BURPS Unreviewed; 351 AA.
AC Q63YS1;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE SubName: Full=LysR family transcription regulatory protein {ECO:0000313|EMBL:CAH34103.1};
GN OrderedLocusNames=BPSL0117 {ECO:0000313|EMBL:CAH34103.1};
OS Burkholderia pseudomallei (strain K96243).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=272560 {ECO:0000313|EMBL:CAH34103.1, ECO:0000313|Proteomes:UP000000605};
RN [1] {ECO:0000313|EMBL:CAH34103.1, ECO:0000313|Proteomes:UP000000605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K96243 {ECO:0000313|EMBL:CAH34103.1,
RC ECO:0000313|Proteomes:UP000000605};
RX PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.M., Atkins T.,
RA Crossman L.C., Pitt T., Churcher C., Mungall K., Bentley S.D., Sebaihia M.,
RA Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F.,
RA Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crosset B.,
RA Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H.,
RA Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C.,
RA Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S.,
RA Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT pseudomallei.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; BX571965; CAH34103.1; -; Genomic_DNA.
DR RefSeq; WP_004189230.1; NZ_CP009538.1.
DR RefSeq; YP_106744.1; NC_006350.1.
DR AlphaFoldDB; Q63YS1; -.
DR STRING; 272560.BPSL0117; -.
DR GeneID; 56596714; -.
DR KEGG; bps:BPSL0117; -.
DR PATRIC; fig|272560.51.peg.1607; -.
DR eggNOG; COG0583; Bacteria.
DR Proteomes; UP000000605; Chromosome 1.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08422; PBP2_CrgA_like; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30537:SF5; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TTDR-RELATED; 1.
DR PANTHER; PTHR30537; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000605}.
FT DOMAIN 1..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
FT REGION 327..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 351 AA; 38828 MW; 136416F7DE8DAE40 CRC64;
MDHLQSMRVF VKVADLGSFA RAASAMDISN AVATRHVADL EGRLGTRLLN RTTRSLSLTE
SGQVYLERAR QILDELEDVE QMVVARNHEP VGTLRVVAPV VFGLHNLAPV LQTYTQRFPK
VIPDLTLVDR QVDLVEEGFD VGIVITRQMR SASIVTRRLT TGCMVVCATP SYLEKHGMPT
HPEQLVEHPC LSLPSEYWGD ERVFTGPDGE VRVRPSNVVV ANNTEMLRQF AMLGMGVAIL
PSYLIGSDIA RGKLVRLLSD YRLPQVEINI AYPSRRHLPA KVRTFIDHLV EHFSQSPDTM
LGEQWATQGV AGQHVDALPA DALAERSSAD PALSPRLPRA PRARTVVPSP L
//
