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Database: UniProt
Entry: Q65SS8
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Original site: Q65SS8 
ID   NRDR_MANSM              Reviewed;         149 AA.
AC   Q65SS8;
DT   15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   01-OCT-2014, entry version 67.
DE   RecName: Full=Transcriptional repressor NrdR {ECO:0000255|HAMAP-Rule:MF_00440};
GN   Name=nrdR {ECO:0000255|HAMAP-Rule:MF_00440}; OrderedLocusNames=MS1375;
OS   Mannheimia succiniciproducens (strain MBEL55E).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Basfia.
OX   NCBI_TaxID=221988;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MBEL55E;
RX   PubMed=15378067; DOI=10.1038/nbt1010;
RA   Hong S.H., Kim J.S., Lee S.Y., In Y.H., Choi S.S., Rih J.-K.,
RA   Kim C.H., Jeong H., Hur C.G., Kim J.J.;
RT   "The genome sequence of the capnophilic rumen bacterium Mannheimia
RT   succiniciproducens.";
RL   Nat. Biotechnol. 22:1275-1281(2004).
CC   -!- FUNCTION: Negatively regulates transcription of bacterial
CC       ribonucleotide reductase nrd genes and operons by binding to NrdR-
CC       boxes. {ECO:0000255|HAMAP-Rule:MF_00440}.
CC   -!- COFACTOR: Binds 1 zinc ion. {ECO:0000255|HAMAP-Rule:MF_00440}.
CC   -!- SIMILARITY: Belongs to the NrdR family. {ECO:0000255|HAMAP-
CC       Rule:MF_00440}.
CC   -!- SIMILARITY: Contains 1 ATP-cone domain. {ECO:0000255|HAMAP-
CC       Rule:MF_00440}.
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DR   EMBL; AE016827; AAU37982.1; -; Genomic_DNA.
DR   RefSeq; YP_088567.1; NC_006300.1.
DR   STRING; 221988.MS1375; -.
DR   EnsemblBacteria; AAU37982; AAU37982; MS1375.
DR   GeneID; 3076702; -.
DR   KEGG; msu:MS1375; -.
DR   PATRIC; 22446061; VBIManSuc86752_1255.
DR   eggNOG; COG1327; -.
DR   HOGENOM; HOG000097653; -.
DR   KO; K07738; -.
DR   OMA; KRRFTTY; -.
DR   OrthoDB; EOG6XM7J6; -.
DR   BioCyc; BMAN221988:GHGM-1417-MONOMER; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   HAMAP; MF_00440; NrdR; 1.
DR   InterPro; IPR005144; ATP-cone.
DR   InterPro; IPR003796; RNR_NrdR-like.
DR   Pfam; PF03477; ATP-cone; 1.
DR   TIGRFAMs; TIGR00244; TIGR00244; 1.
DR   PROSITE; PS51161; ATP_CONE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; DNA-binding; Metal-binding;
KW   Nucleotide-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN         1    149       Transcriptional repressor NrdR.
FT                                /FTId=PRO_0000182316.
FT   DOMAIN       49    139       ATP-cone. {ECO:0000255|HAMAP-
FT                                Rule:MF_00440}.
FT   ZN_FING       3     34       {ECO:0000255|HAMAP-Rule:MF_00440}.
SQ   SEQUENCE   149 AA;  17326 MW;  53A74AB7349E1138 CRC64;
     MHCPFCSTEE TKVIDSRLVS DGYQVRRRRE CTKCHERFTT FETAELVVPK IIKNNGMREP
     FNEDKLRRGI QHALEKRPVS ADDVEKAISH ITHQLRATGE REVPSKLVGS LVMEELKKLD
     KVAYIRFASV YLSFENINEF SNEIEKLKD
//
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