ID NRDR_MANSM Reviewed; 149 AA.
AC Q65SS8;
DT 15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 01-MAY-2013, entry version 61.
DE RecName: Full=Transcriptional repressor NrdR;
GN Name=nrdR; OrderedLocusNames=MS1375;
OS Mannheimia succiniciproducens (strain MBEL55E).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Basfia.
OX NCBI_TaxID=221988;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MBEL55E;
RX PubMed=15378067; DOI=10.1038/nbt1010;
RA Hong S.H., Kim J.S., Lee S.Y., In Y.H., Choi S.S., Rih J.-K.,
RA Kim C.H., Jeong H., Hur C.G., Kim J.J.;
RT "The genome sequence of the capnophilic rumen bacterium Mannheimia
RT succiniciproducens.";
RL Nat. Biotechnol. 22:1275-1281(2004).
CC -!- FUNCTION: Negatively regulates transcription of bacterial
CC ribonucleotide reductase nrd genes and operons by binding to NrdR-
CC boxes (By similarity).
CC -!- COFACTOR: Binds 1 zinc ion (By similarity).
CC -!- SIMILARITY: Belongs to the NrdR family.
CC -!- SIMILARITY: Contains 1 ATP-cone domain.
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DR EMBL; AE016827; AAU37982.1; -; Genomic_DNA.
DR RefSeq; YP_088567.1; NC_006300.1.
DR STRING; 221988.MS1375; -.
DR EnsemblBacteria; AAU37982; AAU37982; MS1375.
DR GeneID; 3076702; -.
DR KEGG; msu:MS1375; -.
DR PATRIC; 22446061; VBIManSuc86752_1255.
DR eggNOG; COG1327; -.
DR HOGENOM; HOG000097653; -.
DR KO; K07738; -.
DR OMA; VCHERFT; -.
DR ProtClustDB; PRK00464; -.
DR BioCyc; BMAN221988:GHGM-1370-MONOMER; -.
DR GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:HAMAP.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:HAMAP.
DR GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR HAMAP; MF_00440; NrdR; 1; -.
DR InterPro; IPR005144; ATP-cone.
DR InterPro; IPR003796; RNR_NrdR-like.
DR Pfam; PF03477; ATP-cone; 1.
DR TIGRFAMs; TIGR00244; TIGR00244; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; DNA-binding; Metal-binding;
KW Nucleotide-binding; Repressor; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1 149 Transcriptional repressor NrdR.
FT /FTId=PRO_0000182316.
FT DOMAIN 49 139 ATP-cone.
FT ZN_FING 3 34 By similarity.
SQ SEQUENCE 149 AA; 17326 MW; 53A74AB7349E1138 CRC64;
MHCPFCSTEE TKVIDSRLVS DGYQVRRRRE CTKCHERFTT FETAELVVPK IIKNNGMREP
FNEDKLRRGI QHALEKRPVS ADDVEKAISH ITHQLRATGE REVPSKLVGS LVMEELKKLD
KVAYIRFASV YLSFENINEF SNEIEKLKD
//
