ID Q66IS3_XENLA Unreviewed; 409 AA.
AC Q66IS3;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=MGC85260 protein {ECO:0000313|EMBL:AAH81221.1};
DE SubName: Full=Proline-serine-threonine phosphatase interacting protein 1 S homeolog {ECO:0000313|RefSeq:NP_001087785.1};
GN Name=pstpip1.S {ECO:0000313|RefSeq:NP_001087785.1,
GN ECO:0000313|Xenbase:XB-GENE-960790};
GN Synonyms=cd2bp1 {ECO:0000313|RefSeq:NP_001087785.1}, cd2bp1l
GN {ECO:0000313|RefSeq:NP_001087785.1}, cd2bp1s
GN {ECO:0000313|RefSeq:NP_001087785.1}, h-pip
GN {ECO:0000313|RefSeq:NP_001087785.1}, MGC85260
GN {ECO:0000313|EMBL:AAH81221.1}, papas
GN {ECO:0000313|RefSeq:NP_001087785.1}, pstpip
GN {ECO:0000313|RefSeq:NP_001087785.1}, pstpip1
GN {ECO:0000313|RefSeq:NP_001087785.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH81221.1};
RN [1] {ECO:0000313|RefSeq:NP_001087785.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH81221.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole {ECO:0000313|EMBL:AAH81221.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001087785.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; BC081221; AAH81221.1; -; mRNA.
DR RefSeq; NP_001087785.1; NM_001094316.2.
DR GeneID; 447609; -.
DR KEGG; xla:447609; -.
DR AGR; Xenbase:XB-GENE-960790; -.
DR CTD; 447609; -.
DR Xenbase; XB-GENE-960790; pstpip1.S.
DR OrthoDB; 3740727at2759; -.
DR Proteomes; UP000186698; Chromosome 3S.
DR Bgee; 447609; Expressed in spleen and 11 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd07671; F-BAR_PSTPIP1; 1.
DR CDD; cd11824; SH3_PSTPIP1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR030777; PSTPIP1_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR23065:SF51; PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 2: Evidence at transcript level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 4..263
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 352..409
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 154..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 409 AA; 46850 MW; BA9695FC4D69026B CRC64;
MTGQEFKNAF WCTDITLNTG YEILLQRLLD GRKMCKDVED LLKQRAQAEE KYGKELVQIA
KKAGGQTEIN KLWKSFKTLK KQIENIGNSH IQLAVTLREE IRSLEEFRER QKEIRKKYEN
SMEHLQKKKV SLYKKTMDSK KSYEQRCQEA KEAEQNHGRL VSLGNPKQIE KSQNKAKHCR
EDAEEADRLY KNNIDFLDKA RIEWETEHIN TCQAFQLQEI DRISILRNSL WVQCNHFSSQ
CVHDDELMEE VRQTLEQCDV NAEIDFFIQS KTTGTVPPEP VLYEGYCNGF APESTIGSNT
QGASTKMVKR ISNLLYGCGG STKNITGHPA VITTTAGKEE IVYASLPTAP AEELEDYSVL
YDYNAQNSDE LDITTGDVVK VIEEADDGWW TVERNGHIGL VPGSYLEKL
//
